Inflammation and preterm birth

M Cappelletti, S Della Bella, E Ferrazzi… - Journal of Leucocyte …, 2016 - academic.oup.com
Preterm birth is the leading cause of neonatal morbidity and mortality. Although the
underlying causes of pregnancy-associated complication are numerous, it is well …

[PDF][PDF] Preterm birth: causes, consequences, and prevention

RE Behrman, AS Butler - 2007 - cds.psych.ucla.edu
Although individual behaviors have not been proven to have a strong influence on the risk of
preterm birth, consistent evidence suggests that a constellation of favorable lifestyle factors …

The Th1: th2 dichotomy of pregnancy and preterm labour

L Sykes, DA MacIntyre, XJ Yap, TG Teoh… - Mediators of …, 2012 - Wiley Online Library
Pregnancy is a unique immunological state in which a balance of immune tolerance and
suppression is needed to protect the fetus without compromising the mother. It has long …

Antibiotics for treating bacterial vaginosis in pregnancy

P Brocklehurst, A Gordon, E Heatley… - Cochrane Database of …, 2013 - cochranelibrary.com
Background Bacterial vaginosis is an imbalance of the normal vaginal flora with an
overgrowth of anaerobic bacteria and a lack of the normal lactobacillary flora. Women may …

Spontaneous preterm birth: advances toward the discovery of genetic predisposition

JF Strauss III, R Romero, N Gomez-Lopez… - American journal of …, 2018 - Elsevier
Evidence from family and twin-based studies provide strong support for a significant
contribution of maternal and fetal genetics to the timing of parturition and spontaneous …

Spontaneous preterm birth, a clinical dilemma: etiologic, pathophysiologic and genetic heterogeneities and racial disparity

R Menon - Acta obstetricia et gynecologica Scandinavica, 2008 - Taylor & Francis
Preterm labor leading to preterm delivery (< 37 weeks' gestation) affects approximately 5–
7% of live births in developed countries, but significantly higher in developing countries …

The determinant role of IL-6 in the establishment of inflammation leading to spontaneous preterm birth

E Prairie, F Cote, M Tsakpinoglou, M Mina… - Cytokine & growth factor …, 2021 - Elsevier
Preterm birth (PTB) and its consequences are a major public health concern as preterm
delivery is the main cause of mortality and morbidity at birth. There are many causes of PTB …

The use of high‐dimensional biology (genomics, transcriptomics, proteomics, and metabolomics) to understand the preterm parturition syndrome

R Romero, J Espinoza, F Gotsch… - … Journal of Obstetrics …, 2006 - Wiley Online Library
High‐dimensional biology (HDB) refers to the simultaneous study of the genetic variants
(DNA variation), transcription (messenger RNA [mRNA]), peptides and proteins, and …

Mannose‐binding lectin: biology and clinical implications

DL Worthley, PG Bardy… - Internal medicine journal, 2005 - Wiley Online Library
The innate host defence molecule mannose‐binding lectin (MBL) has attracted great interest
as a potential candidate for passive immunotherapy to prevent infection. MBL is a multimeric …

Genetic contributions to preterm birth: implications from epidemiological and genetic association studies

J Plunkett, LJ Muglia - Annals of medicine, 2008 - Taylor & Francis
Infants born before term (< 37 weeks) have an increased risk of neonatal mortality as well as
other health problems. The increasing rate of preterm birth in recent decades, despite …