[HTML][HTML] Glioma stem cells: novel data obtained by single-cell sequencing

A Gisina, I Kholodenko, Y Kim, M Abakumov… - International journal of …, 2022 - mdpi.com
Glioma is the most common type of primary CNS tumor, composed of cells that resemble
normal glial cells. Recent genetic studies have provided insight into the inter-tumoral …

[HTML][HTML] The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic …

SM Faisal, A Comba, ML Varela, AE Argento… - Frontiers in …, 2022 - frontiersin.org
Glioblastoma (GBM), an aggressive high-grade glial tumor, is resistant to therapy and has a
poor prognosis due to its universal recurrence rate. GBM cells interact with the non-cellular …

Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions

J Zhou, L Li, M Jia, Q Liao, G Peng, G Luo… - Cancer …, 2023 - Wiley Online Library
Introduction Gliomas, especially the glioblastomas, are one of the most aggressive
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …

[HTML][HTML] Molecular pathways and genomic landscape of glioblastoma stem cells: opportunities for targeted therapy

AM Hersh, H Gaitsch, S Alomari, D Lubelski, BM Tyler - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma stem cells are a unique population of tumor cells that
contribute to tumor growth, invasion, and resistance to chemotherapy and radiation therapy …

[HTML][HTML] Tumor microenvironment and glioblastoma cell interplay as promoters of therapeutic resistance

E Agosti, PP Panciani, M Zeppieri, L De Maria… - Biology, 2023 - mdpi.com
Simple Summary Despite years of molecular discoveries and technological advances in
surgery, the prognosis of glioblastoma (GBM) still remains unfavorable, with a mean overall …

[HTML][HTML] Neurotransmitters: potential targets in glioblastoma

Q Huang, L Chen, J Liang, Q Huang, H Sun - Cancers, 2022 - mdpi.com
Simple Summary Aiming to discover potential treatments for GBM, this review connects
emerging research on the roles of neurotransmitters in the normal neural and the GBM …

[HTML][HTML] Pericyte–glioblastoma cell interaction: A key target to prevent glioblastoma progression

A Pombero, R Garcia-Lopez, S Martínez - Cells, 2023 - mdpi.com
Multiple biological processes rely on direct intercellular interactions to regulate cell
proliferation and migration in embryonic development and cancer processes. Tumor …

HDAC1 mediates epithelial–mesenchymal transition and promotes cancer cell invasion in glioblastoma

Z Cheng, S Li, J Yuan, Y Li, S Cheng, S Huang… - … -Research and Practice, 2023 - Elsevier
Glioblastoma multiforme (GBM) is one of the most malignant tumors of the central nervous
system, and its treatment has always been a difficult clinical problem. Here, we evaluated …

[HTML][HTML] Unravelling the glioblastoma tumour microenvironment: Can aptamer targeted delivery become successful in treating brain cancers?

B Giles, M Nakhjavani, A Wiesa, T Knight, S Shigdar… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme is the most lethal form of brain cancer. To improve
patient outcomes, more effective treatments should be designed. Therefore, it is important to …

[HTML][HTML] The role of angiogenic growth factors in the immune microenvironment of glioma

Z Ge, Q Zhang, W Lin, X Jiang, Y Zhang - Frontiers in Oncology, 2023 - ncbi.nlm.nih.gov
Angiogenic growth factors (AGFs) are a class of secreted cytokines related to angiogenesis
that mainly include vascular endothelial growth factors (VEGFs), stromal-derived factor-1 …