In young adults, up to 20% of all cases of sudden death are due to myocarditis, a heart
disease caused by inflammation in the myocardium. There are several reasons that lead to …

Biological systems are typically complex and adaptive, involving large numbers of entities,
or organisms, and many-layered interactions between these. System behaviour evolves …

自1981 年发现首例人类获得性免疫缺失综合症(艾滋病, AIDS) 至今已有30 多年,
然而人们至今未能找到治疗这种危及人类生命健康的可怕疾病的方法. 建立正确的艾滋病病毒 …

Despite increasing knowledge about pathophysiological pathways and cellular processes
involved in diseases, the molecular mechanisms and physiological significance are not fully …

Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through
its interactions with growing and decaying flora and their constituent microbiomes. The …

In the past 30 years, HIV infection made a transition from fatal to chronic disease due to the
emergence of potent treatment largely suppressing viral replication. However, this …

Multi-layered model of individual HIV infection progression and mechanisms of
phenotypical expression Dimitri Perrin Page 1 This text in white does not appear but permits …

This paper proposes an agent-based model of the action of macrophages on the beta cells
of the endocrine pancreas. The aim of this model is to simulate the processes of beta cell …

We live in a complex world. Many of the worlds current problems or natural phenomena can
be described as complex, from protein-protein interactions [179] and spreading of infectious …

In the present work we have developed an agent-based model of the interaction between
the beta cells of the endocrine pancreas and the macrophages of the innate immune system …