Wastewater-based surveillance as a tool for public health action: SARS-CoV-2 and beyond

MD Parkins, BE Lee, N Acosta, M Bautista… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …

Recent advances in molecular and immunological diagnostic platform for virus detection: A review

KTL Trinh, HDK Do, NY Lee - Biosensors, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an ongoing
coronavirus disease (COVID-19) outbreak and a rising demand for the development of …

Identification and validation of fusidic acid and flufenamic acid as inhibitors of SARS-CoV-2 replication using DrugSolver CavitomiX

M Hetmann, C Langner, V Durmaz, M Cespugli… - Scientific Reports, 2023 - nature.com
In this work, we present DrugSolver CavitomiX, a novel computational pipeline for drug
repurposing and identifying ligands and inhibitors of target enzymes. The pipeline is based …

Artificial intelligence for diagnosis of mild–moderate COVID-19 using haematological markers

K Chadaga, S Prabhu, V Bhat, N Sampathila… - Annals of …, 2023 - Taylor & Francis
Objective The persistent spread of SARS-CoV-2 makes diagnosis challenging because
COVID-19 symptoms are hard to differentiate from those of other respiratory illnesses. The …

Bio-conjugated nanoarchitectonics with dual-labeled nanoparticles for a colorimetric and fluorescent dual-mode serological lateral flow immunoassay sensor in …

SK Kim, JU Lee, MJ Jeon, SK Kim, SH Hwang… - RSC …, 2023 - pubs.rsc.org
Serological detection of antibodies for diagnosing infectious diseases has advantages in
facile diagnostic procedures, thereby contributing to controlling the spread of the pathogen …

Nucleic Acid Amplification-Free Digital Detection Method for SARS-CoV-2 RNA Based on Droplet Microfluidics and CRISPR–Cas13a

X Shan, F Gong, Y Yang, J Qian, Z Tan, S Tian… - Analytical …, 2023 - ACS Publications
Most of the methods currently developed for RNA detection based on CRISPR were
combined with nucleic acid amplification. As a result, such methods inevitably led to certain …

Machine learning techniques for effective pathogen detection based on resonant biosensors

G Rong, Y Xu, M Sawan - Biosensors, 2023 - mdpi.com
We describe a machine learning (ML) approach to processing the signals collected from a
COVID-19 optical-based detector. Multilayer perceptron (MLP) and support vector machine …

Harnessing of artificial intelligence for the diagnosis and prevention of hospital-acquired infections: a systematic review

B Baddal, F Taner, D Uzun Ozsahin - Diagnostics, 2024 - mdpi.com
Healthcare-associated infections (HAIs) are the most common adverse events in healthcare
and constitute a major global public health concern. Surveillance represents the foundation …

Recombinase polymerase amplification combined with fluorescence immunochromatography assay for on-site and ultrasensitive detection of SARS-CoV-2

G Wang, X Yang, H Dong, Z Tu, Y Zhou, Z Rong… - Pathogens, 2022 - mdpi.com
This study established a portable and ultrasensitive detection method based on
recombinase polymerase amplification (RPA) combined with high-sensitivity multilayer …

The deceptive COVID-19: lessons from common molecular diagnostics and a novel plan for the prevention of the next pandemic

DS Mouliou - Diseases, 2023 - mdpi.com
The COVID-19 pandemic took place during the years 2020–2022 and the virus, named
SARS-CoV-2, seems likely to have resulted in an endemic disease. Nevertheless …