Gait impairments in Parkinson's disease

A Mirelman, P Bonato, R Camicioli, TD Ellis… - The Lancet …, 2019 - thelancet.com
Gait impairments are among the most common and disabling symptoms of Parkinson's
disease. Nonetheless, gait is not routinely assessed quantitatively but is described in …

Freezing of gait in Parkinson's disease: pathophysiology, risk factors and treatments

C Gao, J Liu, Y Tan, S Chen - Translational neurodegeneration, 2020 - Springer
Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …

A systematic review on exercise and training-based interventions for freezing of gait in Parkinson's disease

M Gilat, P Ginis, D Zoetewei… - npj Parkinson's …, 2021 - nature.com
Freezing of gait (FOG) in Parkinson's disease (PD) causes severe patient burden despite
pharmacological management. Exercise and training are therefore advocated as important …

Compensation strategies for gait impairments in Parkinson disease: a review

J Nonnekes, E Růžička, A Nieuwboer, M Hallett… - JAMA …, 2019 - jamanetwork.com
Importance Patients with Parkinson disease can use a wide variety of strategies to
compensate for their gait impairments. Examples include walking while rhythmically …

Clinical and methodological challenges for assessing freezing of gait: future perspectives

M Mancini, BR Bloem, FB Horak, SJG Lewis… - Movement …, 2019 - Wiley Online Library
Freezing of gait, defined as sudden and usually brief episodes of inability to produce
effective stepping, often results in falls and is both disabling and common in parkinsonism. In …

Prediction and detection of freezing of gait in Parkinson's disease from plantar pressure data using long short-term memory neural-networks

G Shalin, S Pardoel, ED Lemaire, J Nantel… - … of neuroengineering and …, 2021 - Springer
Background Freezing of gait (FOG) is a walking disturbance in advanced stage Parkinson's
disease (PD) that has been associated with increased fall risk and decreased quality of life …

Detection and assessment of Parkinson's disease based on gait analysis: A survey

Y Guo, J Yang, Y Liu, X Chen, GZ Yang - Frontiers in aging …, 2022 - frontiersin.org
Neurological disorders represent one of the leading causes of disability and mortality in the
world. Parkinson's Disease (PD), for example, affecting millions of people worldwide is often …

Slowly evolving dopaminergic activity modulates the moment-to-moment probability of reward-related self-timed movements

AE Hamilos, G Spedicato, Y Hong, F Sun, Y Li… - Elife, 2021 - elifesciences.org
Clues from human movement disorders have long suggested that the neurotransmitter
dopamine plays a role in motor control, but how the endogenous dopaminergic system …

Managing gait, balance, and posture in Parkinson's disease

B Debû, C De Oliveira Godeiro, JC Lino… - Current neurology and …, 2018 - Springer
Abstract Purpose of Review Postural instability and gait difficulties inexorably worsen with
Parkinson's disease (PD) progression and become treatment resistant, with a severe impact …

Exercise for Parkinson's disease

MKY Mak, ISK Wong-Yu - International review of neurobiology, 2019 - Elsevier
Parkinson's disease is the second most common neurodegenerative disease with a
prevalence rate of 1–2 per 1000 of the population worldwide. Pharmacological management …