[HTML][HTML] Artificial intelligence in cervical cancer screening and diagnosis

X Hou, G Shen, L Zhou, Y Li, T Wang, X Ma - Frontiers in oncology, 2022 - frontiersin.org
Cervical cancer remains a leading cause of cancer death in women, seriously threatening
their physical and mental health. It is an easily preventable cancer with early screening and …

[HTML][HTML] Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine

C Xue, Q Chu, Q Zheng, S Jiang, Z Bao, Y Su… - Signal transduction and …, 2022 - nature.com
Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

[HTML][HTML] Hybrid AI-assistive diagnostic model permits rapid TBS classification of cervical liquid-based thin-layer cell smears

X Zhu, X Li, K Ong, W Zhang, W Li, L Li… - Nature …, 2021 - nature.com
Technical advancements significantly improve earlier diagnosis of cervical cancer, but
accurate diagnosis is still difficult due to various factors. We develop an artificial intelligence …

[HTML][HTML] The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells

D Zou, L Dong, C Li, Z Yin, S Rao, Q Zhou - Cancer cell international, 2019 - Springer
Background Since FTO was recognized as the first m 6 A demethylase, the understanding of
its biological function has been widely expanded. However, the role of FTO in cervical …

The looming geriatrician shortage: ramifications and solutions

PE Lester, TS Dharmarajan… - Journal of aging and …, 2020 - journals.sagepub.com
Objective: Geriatricians are skilled in the recognition of asymptomatic and atypical
presentations that occur in the elderly and provide comprehensive medication management …

[HTML][HTML] Diagnostic accuracy of cytology for the detection of endometrial cancer in urine and vaginal samples

H O'Flynn, NAJ Ryan, N Narine, D Shelton… - Nature …, 2021 - nature.com
Postmenopausal bleeding triggers urgent investigation by sequential invasive tests that are
avoidable for the 90–95% of women who do not have endometrial cancer. A simple, non …

[HTML][HTML] Comprehensive characterization of tumor microenvironment and m6A RNA methylation regulators and its effects on PD-L1 and immune infiltrates in cervical …

H Ji, J Zhang, H Liu, K Li, Z Wang, X Zhu - Frontiers in Immunology, 2022 - frontiersin.org
Understanding the role of N6-adenosine methylation (m6A) in the tumor microenvironment
(TME) is important since it can contribute to tumor development. However, the research …

Extracellular vesicles-encapsulated microRNA-10a-5p shed from cancer-associated fibroblast facilitates cervical squamous cell carcinoma cell angiogenesis and …

X Zhang, Y Wang, X Wang, B Zou, J Mei, X Peng… - Cancer gene …, 2021 - nature.com
Cancer-associated fibroblast (CAF) secretes extracellular vesicle (EV)-encapsulated
microRNAs (miRNAs) which have been underlined great promise for therapeutic target for …

[HTML][HTML] Development and validation of an m6A RNA methylation regulator-based signature for prognostic prediction in cervical squamous cell carcinoma

J Pan, L Xu, H Pan - Frontiers in Oncology, 2020 - frontiersin.org
Background: Cervical squamous cell carcinoma (CESC) is one of the most common causes
of cancer-related death worldwide. N6-methyladenosine (m6A) plays an important role in …

[HTML][HTML] Colposcopic accuracy in diagnosing squamous intraepithelial lesions: a systematic review and meta-analysis of the International Federation of Cervical …

D Qin, A Bai, P Xue, S Seery, J Wang, MJG Mendez… - BMC cancer, 2023 - Springer
Background Colposcopy is an important tool in diagnosing cervical cancer, and the
International Federation of Cervical Pathology and Colposcopy (IFCPC) issued the latest …