Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

Transcriptional regulation is essential for the correct functioning of cells during development
and in postnatal life. The basic Helix-loop-Helix (bHLH) superfamily of transcription factors is …

One goal of genomic medicine is to uncover an individual's genetic risk for disease, which
generally requires data connecting genotype to phenotype, as done in genome-wide …

Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Inborn errors of immunity (IEIs) are immunological disorders characterized by variable
susceptibility to infections, immune dysregulation and/or malignancies, as a consequence of …

Traditionally, heritability has been estimated using family-based methods such as twin
studies. Advancements in molecular genomics have facilitated the development of methods …

Clinically and biologically, rare DNA sequence variants are significant and informative.
However, existing common detection technologies are either complex and time-consuming …

The development of improved methods for genome‐wide association studies (GWAS) for
genetics of quantitative traits has been an active area of research during the last 25 years …

Background: Whole-genome sequencing has become routine for population genetic studies.
Sequencing of individuals provides maximal data but is rather expensive and fewer samples …