[HTML][HTML] Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets

C Wang, Z Li, Y Liu, L Yuan - Theranostics, 2021 - ncbi.nlm.nih.gov
Exosomes are nanosized lipid vesicles originating from the endosomal system that carry
many macromolecules from their parental cells and play important roles in intercellular …

Circular RNAs: expression, localization, and therapeutic potentials

Q Yang, F Li, AT He, BB Yang - Molecular therapy, 2021 - cell.com
Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …

Exosomes derived from mmu_circ_0000250-modified adipose-derived mesenchymal stem cells promote wound healing in diabetic mice by inducing miR-128-3p …

R Shi, Y Jin, W Hu, W Lian, C Cao… - … of Physiology-Cell …, 2020 - journals.physiology.org
More and more evidence advises that circular RNAs (circRNAs) function critically in
regulating different disease microenvironments. Our previous study found that …

The potential of using blood circular RNA as liquid biopsy biomarker for human diseases

G Wen, T Zhou, W Gu - Protein & cell, 2021 - academic.oup.com
Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …

Circular RNAs in the pathogenesis of atherosclerosis

Q Cao, Z Guo, S Du, H Ling, C Song - Life sciences, 2020 - Elsevier
Atherosclerosis is a common cause of cardiovascular and cerebrovascular diseases.
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs), long noncoding RNAs …

CircNPHP4 in monocyte-derived small extracellular vesicles controls heterogeneous adhesion in coronary heart atherosclerotic disease

F Xiong, R Mao, L Zhang, R Zhao, K Tan, C Liu… - Cell death & …, 2021 - nature.com
Small extracellular vesicles (sEVs)-derived circular RNAs (circRNAs) could regulate gene
expression in recipient cells, and dysregulation of sEVs-derived circRNAs has been …

Potential second-hits in hereditary hemorrhagic telangiectasia

C Bernabeu, P Bayrak-Toydemir, J McDonald… - Journal of Clinical …, 2020 - mdpi.com
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder
that presents with telangiectases in skin and mucosae, and arteriovenous malformations …

Circular RNA circ_0010283 regulates the viability and migration of oxidized low‑density lipoprotein‑induced vascular smooth muscle cells via an miR‑370‑3p/HMGB1 …

P Ding, Y Ding, Y Tian, X Lei - … Journal of Molecular …, 2020 - spandidos-publications.com
Atherosclerosis is a disease during which the inside of an artery narrows due to the
accumulation of plaque, and vascular smooth muscle cells (VSMCs) are involved in the …

circRNA is a potential target for cardiovascular diseases treatment

J Ju, Y Song, X Chen, T Wang, C Liu… - Molecular and Cellular …, 2022 - Springer
Circular RNAs (circRNAs), a novel class of endogenous noncoding RNA, are characterized
by their covalently closed-loop structures without a 5′ cap or a 3′ poly (A) tail. With the …

A circular RNA, circUSP36, accelerates endothelial cell dysfunction in atherosclerosis by adsorbing miR-637 to enhance WNT4 expression

J Huang, X Tang, J Wang, J Liu, P Chen, Y Sun - Bioengineered, 2021 - Taylor & Francis
Atherosclerosis is a fatal disorder that is fundamental to various cardiovascular diseases
and severely threatens people's health worldwide. Several studies have demonstrated the …