Pathogenesis, multi-omics research, and clinical treatment of psoriasis

J Yu, Q Zhao, X Wang, H Zhou, J Hu, L Gu, Y Hu… - Journal of …, 2022 - Elsevier
Psoriasis is a common inflammatory skin disease involving interactions between
keratinocytes and immune cells that significantly affects the quality of life. It is characterized …

[HTML][HTML] N6-methyladenosine modification opens a new chapter in circular RNA biology

J Wu, X Guo, Y Wen, S Huang, X Yuan… - Frontiers in cell and …, 2021 - frontiersin.org
As the most abundant internal modification in eukaryotic cells, N6-methyladenosine (m6A) in
mRNA has shown widespread regulatory roles in a variety of physiological processes and …

Epigenetic regulation of cellular functions in wound healing

I Pastar, J Marjanovic, RC Stone, V Chen… - Experimental …, 2021 - Wiley Online Library
Stringent spatiotemporal regulation of the wound healing process involving multiple cell
types is associated with epigenetic mechanisms of gene regulation, such as DNA …

[HTML][HTML] Exosomal circular RNAs: New player in breast cancer progression and therapeutic targets

BM Hussen, S Mohamadtahr, SR Abdullah… - Frontiers in …, 2023 - frontiersin.org
Breast cancer is the most prevalent type of malignancy among women. Exosomes are
extracellular vesicles of cell membrane origin that are released via exocytosis. Their cargo …

[HTML][HTML] Identification of Novel Circular RNAs of the Human Protein Arginine Methyltransferase 1 (PRMT1) Gene, Expressed in Breast Cancer Cells

M Papatsirou, MA Diamantopoulos, K Katsaraki… - Genes, 2022 - mdpi.com
Circular RNAs (circRNAs) constitute a type of RNA formed through back-splicing. In breast
cancer, circRNAs are implicated in tumor onset and progression. Although histone …

Adipocyte-derived exosomes promote the progression of triple-negative breast cancer through circCRIM1-dependent OGA activation

Y Li, B Jiang, L Zeng, Y Tang, X Qi, Z Wan… - Environmental …, 2023 - Elsevier
Triple-negative breast cancer (TNBC) has an escalating morbidity and a dismal prognosis.
Obesity has been reported to be strongly linked to adverse TNBC outcomes. Exosomes …

[HTML][HTML] Expression and Regulatory Mechanisms of MicroRNA in Cholesteatoma: A Systematic Review

K Dżaman, K Czerwaty, TE Reichert… - International Journal of …, 2023 - mdpi.com
Cholesteatoma is a temporal bone disease characterized by dysfunctions of keratinocytes.
MicroRNAs (miRNAs) are evolutionary conserved noncoding RNAs that regulate mRNA …

Beyond the code: noncoding RNAs in skin wound healing

D Li, G Niu, NX Landén - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
An increasing number of noncoding RNAs (ncRNAs) have been found to regulate gene
expression and protein functions, playing important roles in diverse biological processes …

Non-coding RNAs in photoaging-related mechanisms: a new paradigm in skin health

MH Soheilifar, N Masoudi-Khoram, A Shirkavand… - Biogerontology, 2022 - Springer
The aging of skin is a biological process affected by environmental or genetic factors.
Exposure to ultraviolet (UV) radiation is the main environmental factor causing skin aging …

[HTML][HTML] Circular RNA ZNF609 drives tumor progression by regulating the miR-138-5p/SIRT7 axis in melanoma

Q Liu, W Cui, C Yang, LP Du - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Melanoma serves as a prevailing and lethal skin malignancy with high mortality and a
growing number of patients globally. Circular RNAs (circRNAs), as a type of emerging …