Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection

N Le Bert, HE Clapham, AT Tan, WN Chia… - Journal of Experimental …, 2021 - rupress.org
The efficacy of virus-specific T cells in clearing pathogens involves a fine balance between
antiviral and inflammatory features. SARS-CoV-2–specific T cells in individuals who clear …

[HTML][HTML] Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

CY Lin, J Wolf, DC Brice, Y Sun, M Locke, S Cherry… - Cell Host & Microbe, 2022 - cell.com
SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to
respiratory distress and death. A major unresolved question is whether prior immunity to …

Rapid and sensitive SERS-based lateral flow test for SARS-CoV2-specific IgM/IgG antibodies

S Srivastav, A Dankov, M Adanalic… - Analytical …, 2021 - ACS Publications
As an immune response to COVID-19 infection, patients develop SARS-CoV-2-specific
IgM/IgG antibodies. Here, we compare the performance of a conventional lateral flow assay …

Differential T-cell reactivity to endemic coronaviruses and SARS-CoV-2 in community and health care workers

R da Silva Antunes, S Pallikkuth… - The Journal of …, 2021 - academic.oup.com
Herein we measured CD4+ T-cell responses against common cold coronaviruses (CCC)
and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in high-risk health care …

Relative ratios of human seasonal coronavirus antibodies predict the efficiency of cross-neutralization of SARS-CoV-2 spike binding to ACE2

Y Galipeau, V Siragam, G Laroche, E Marion… - …, 2021 - thelancet.com
Background Antibodies raised against human seasonal coronaviruses (sCoVs), which are
responsible for the common cold, are known to cross-react with SARS-CoV-2 antigens. This …

More than just gene therapy vectors: Lentiviral vector pseudotypes for serological investigation

K Toon, EM Bentley, G Mattiuzzo - Viruses, 2021 - mdpi.com
Serological assays detecting neutralising antibodies are important for determining the
immune responses following infection or vaccination and are also often considered a …

The effectiveness of inactivated SARS‐CoV‐2 vaccine (CoronaVac) on antibody response in participants aged 65 years and older

M Karamese, EE Tutuncu - Journal of Medical Virology, 2022 - Wiley Online Library
In this study, it was aimed to determine the antibody responses after the two doses of
inactivated severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccinations in …

Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19

M Yu, A Charles, A Cagigi, W Christ… - Nature …, 2023 - nature.com
Effective humoral immune responses require well-orchestrated B and T follicular helper (Tfh)
cell interactions. Whether these interactions are impaired and associated with COVID-19 …

Long-term course of humoral and cellular immune responses in outpatients after SARS-CoV-2 infection

J Schiffner, I Backhaus, J Rimmele, S Schulz… - Frontiers in Public …, 2021 - frontiersin.org
Characterization of the naturally acquired B and T cell immune responses to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is important for the development of …