Dietary carbohydrates and fats in nonalcoholic fatty liver disease

H Yki-Järvinen, PK Luukkonen, L Hodson… - Nature reviews …, 2021 - nature.com
The global prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …

[HTML][HTML] Current treatment paradigms and emerging therapies for NAFLD/NASH

S Raza, S Rajak, A Upadhyay, A Tewari… - Frontiers in bioscience …, 2021 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is one the fastest emerging manifestations of the
metabolic syndrome worldwide. Non-alcoholic steatohepatitis (NASH), the progressive form …

[HTML][HTML] Palmitic acid: physiological role, metabolism and nutritional implications

G Carta, E Murru, S Banni, C Manca - Frontiers in physiology, 2017 - frontiersin.org
Palmitic acid (PA) has been for long time negatively depicted for its putative detrimental
health effects, shadowing its multiple crucial physiological activities. PA is the most common …

[PDF][PDF] The small intestine converts dietary fructose into glucose and organic acids

C Jang, S Hui, W Lu, AJ Cowan, RJ Morscher, G Lee… - Cell metabolism, 2018 - cell.com
Excessive consumption of sweets is a risk factor for metabolic syndrome. A major chemical
feature of sweets is fructose. Despite strong ties between fructose and disease, the …

[HTML][HTML] “Sweet death”: fructose as a metabolic toxin that targets the gut-liver axis

MA Febbraio, M Karin - Cell metabolism, 2021 - cell.com
Glucose and fructose are closely related simple sugars, but fructose has been associated
more closely with metabolic disease. Until the 1960s, the major dietary source of fructose …

Biomarkers of oxidative stress in metabolic syndrome and associated diseases

R Vona, L Gambardella, C Cittadini… - Oxidative medicine …, 2019 - Wiley Online Library
Metabolic syndrome (MS) represents worldwide public health issue characterized by a set of
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

TJ Park, J Reznick, BL Peterson, G Blass, D Omerbašić… - Science, 2017 - science.org
The African naked mole-rat's (Heterocephalus glaber) social and subterranean lifestyle
generates a hypoxic niche. Under experimental conditions, naked mole-rats tolerate hours …

High-fructose corn syrup enhances intestinal tumor growth in mice

MD Goncalves, C Lu, J Tutnauer, TE Hartman… - Science, 2019 - science.org
Excessive consumption of beverages sweetened with high-fructose corn syrup (HFCS) is
associated with obesity and with an increased risk of colorectal cancer. Whether HFCS …

Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Natural sweeteners: The relevance of food naturalness for consumers, food security aspects, sustainability and health impacts

A Saraiva, C Carrascosa, D Raheem, F Ramos… - International journal of …, 2020 - mdpi.com
At a moment when the population is increasingly aware and involved in what it eats, both
consumers and the food sector are showing more interest in natural foods. This review work …