Performance evaluation of a PCR panel (FilmArray® Pneumonia Plus) for detection of respiratory bacterial pathogens in respiratory specimens: A systematic review …

AC Moy, A Kimmoun, T Merkling, B Berçot… - … Critical Care & Pain …, 2023 - Elsevier
Background Accuracy and timing of antibiotic therapy remain a challenge for lower
respiratory tract infections. New molecular techniques using Multiplex Polymerase Chain …

Diagnostic stewardship: what impacts antibiotics use?

KC Coffey, DJ Morgan, KC Claeys - Current Opinion in Infectious …, 2023 - journals.lww.com
Diagnostic stewardship decreases unnecessary antibiotic use in a way that is different from
and complementary to antibiotic stewardship. Further studies are needed to quantify the full …

Population sepsis incidence, mortality, and trends in Hong Kong between 2009–2018 using clinical and administrative data

L Ling, JZ Zhang, LC Chang, LCS Chiu… - Clinical Infectious …, 2023 - academic.oup.com
Background Sepsis surveillance using electronic health record (EHR)-based data may
provide more accurate epidemiologic estimates than administrative data, but experience …

Diagnostic utility of oropharyngeal swabs as an alternative to lower respiratory tract samples for PCR-based syndromic testing in patients with community-acquired …

S Serigstad, ST Knoop, DL Markussen… - Journal of Clinical …, 2023 - Am Soc Microbiol
Syndromic PCR-based analysis of lower respiratory tract (LRT) samples in patients with
community-acquired pneumonia (CAP) improves the bacterial yield and time-to-results …

Diagnostic stewardship in community-acquired pneumonia with syndromic molecular testing: a randomized clinical trial

DL Markussen, S Serigstad, C Ritz, ST Knoop… - JAMA Network …, 2024 - jamanetwork.com
Importance Lower respiratory tract (LRT) infections, including community-acquired
pneumonia (CAP), are a leading cause of hospital admissions and mortality. Molecular tests …

[HTML][HTML] Ten Issues for Updating in Community-Acquired Pneumonia: An Expert Review

FJ Candel, M Salavert, M Basaras, M Borges… - Journal of Clinical …, 2023 - mdpi.com
Community-acquired pneumonia represents the third-highest cause of mortality in
industrialized countries and the first due to infection. Although guidelines for the approach to …

[HTML][HTML] Optimized Antibiotic Management of Critically Ill Patients with Severe Pneumonia Following Multiplex Polymerase Chain Reaction Testing: A Prospective …

A Verroken, J Favresse, A Anantharajah… - Antibiotics, 2024 - mdpi.com
Molecular diagnostic testing is assumed to enable fast respiratory pathogen identification
and contribute to improved pneumonia management. We set up a prospective clinical trial at …

¿ Cómo podemos optimizar el abordaje diagnóstico y terapéutico de la neumonía? Recomendaciones basadas en una opinión de expertos

M Fernández-Ruiz, JJ Castón, JL del Pozo… - … y Microbiología Clínica, 2024 - Elsevier
La neumonía es uno de los síndromes infecciosos más frecuentes y una importante causa
de mortalidad y de consumo de recursos. Constituido por expertos en Enfermedades …

[HTML][HTML] Microbial aetiology of community-acquired pneumonia in hospitalised adults: A prospective study utilising comprehensive molecular testing

DL Markussen, Ø Kommedal, ST Knoop… - International Journal of …, 2024 - Elsevier
Objectives This study aimed to describe the microbial aetiology of community-acquired
pneumonia (CAP) in adults admitted to a tertiary care hospital and assess the impact of …

[HTML][HTML] Antibiotic Consumption in a Cohort of Hospitalized Adults with Viral Respiratory Tract Infection

S Debes, JB Haug, BF De Blasio, JC Lindstrøm… - Antibiotics, 2023 - mdpi.com
Development of antibiotic resistance, a threat to global health, is driven by inappropriate
antibiotic usage. Respiratory tract infections (RTIs) are frequently treated empirically with …