Single-cell approaches have shone a spotlight on discrete context-specific tissue
macrophage states, deconstructed to their most minute details. Machine-learning (ML) …

The endoplasmic reticulum (ER) is a cellular organelle that is physiologically responsible for
protein folding, calcium homeostasis, and lipid biosynthesis. Pathological stimuli such as …

Introduction Vascular smooth muscle cells (VSMCs) are the predominant cell type in the
medial layer of the aorta, which plays a critical role in aortic diseases. Innate immunity is the …

Acquisition of immunological memory is an important evolutionary strategy that evolved to
protect the host from repetitive challenges from infectious agents. It was believed for a long …

Abdominal aortic aneurysm (AAA) is a chronic aortic disease that lacks effective
pharmacological therapies. This study was performed to determine the influence of …

Cardiovascular diseases are significant contributors to human mortality, closely associated
with inflammation. With the changing living conditions and the extension of human lifespan …

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Highthroughput
metabolomics analysis is a powerful tool in characterizing metabolomic reprogramming …