Chronic kidney disease (CKD) is estimated to affect 10–14% of global population. Kidney
fibrosis, characterized by excessive extracellular matrix deposition leading to scarring, is a …

Kidney disease is a significant health problem worldwide, affecting an estimated 10% of the
global population. Kidney disease encompasses a diverse group of disorders that vary in …

Background: Renal infiltration of inflammatory cells including macrophages is a crucial event
in kidney fibrogenesis. However, how macrophage regulates fibroblast activation in the …

Kidney fibrosis is the hallmark of chronic kidney disease (CKD) progression, whereas no
effective anti-fibrotic therapies exist. Recent evidence has shown that tubular ferroptosis …

Developing a drug delivery platform that possesses universal drug loading capacity to meet
various requirements of cancer treatment is a challenging yet interesting task. Herein, a self …

Background Epigenetics regulating gene expression plays important role in kidney fibrosis.
Natural products originating from diverse sources including plants and microorganisms are …

Renal fibrosis (RF) is the common pathological manifestation of virtually all chronic kidney
diseases (CKD) and one of the major causes of end-stage renal disease (ESRD), but the …

Abstract Ethnopharmacological relevance Yi-Shen-Xie-Zhuo formula (YSXZF) is a traditional
Chinese medicine prescription developed from the classic prescription Mulizexie powder …

Recent studies have indicated that gut microbiota-mediated oxidative stress is significantly
associated with intestinal diseases such as colorectal cancer, ulcerative colitis, and Crohn's …

Background Chronic kidney disease (CKD) is characterized by persistent damage to kidney
function or structure. Progression to end-stage leads to adverse effects on multiple systems …