Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …

Fat tissue, frequently the largest organ in humans, is at the nexus of mechanisms involved in
longevity and age‐related metabolic dysfunction. Fat distribution and function change …

Obesity is associated with low-grade chronic inflammation promoting insulin-resistance and
diabetes. Gut microbiota dysbiosis is a consequence as well as a driver of obesity and …

Adipose tissue plays a central role in regulating whole-body energy and glucose
homeostasis through its subtle functions at both organ and systemic levels. On one hand …

Radiation therapy induces DNA damage and inflammation leading to fibrosis. Fibrosis can
occur 4 to 12 months after radiation therapy. This process worsens with time and years …

Forkhead proteins, and FoxO1 in particular, play a significant role in regulating whole body
energy metabolism. Glucose homeostasis is achieved by adjusting endogenous glucose …

Summary The inositol pyrophosphate IP7 (5-diphosphoinositolpentakisphosphate), formed
by a family of three inositol hexakisphosphate kinases (IP6Ks), modulates diverse cellular …

Chronic diseases account for approximately 45% of all deaths in developed countries and
are particularly prevalent in countries with the most sophisticated and robust public health …

Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases which
lacks ideal treatment options. Kaempferol and kaempferide, two natural flavonol compounds …

Background Obesity is a global health concern with limited treatment options due to side
effects and limited efficacy. Bioactive peptides (BAPs) derived from food proteins have …