Regulation of ATP-dependent chromatin remodelers: accelerators/brakes, anchors and sensors
S Paul, B Bartholomew - Biochemical Society Transactions, 2018 - portlandpress.com
All ATP-dependent chromatin remodelers have a DNA translocase domain that moves along
double-stranded DNA when hydrolyzing ATP, which is the key action leading to DNA …
double-stranded DNA when hydrolyzing ATP, which is the key action leading to DNA …
Autoinhibitory elements of the Chd1 remodeler block initiation of twist defects by destabilizing the ATPase motor on the nucleosome
IM Nodelman, Z Shen… - Proceedings of the …, 2021 - National Acad Sciences
Chromatin remodelers are ATP (adenosine triphosphate)-powered motors that reposition
nucleosomes throughout eukaryotic chromosomes. Remodelers possess autoinhibitory …
nucleosomes throughout eukaryotic chromosomes. Remodelers possess autoinhibitory …
Identification of residues in chromodomain helicase DNA-binding protein 1 (Chd1) required for coupling ATP hydrolysis to nucleosome sliding
Chromatin remodelers are ATP-dependent machines responsible for directionally shifting
nucleosomes along DNA. We are interested in defining which elements of the …
nucleosomes along DNA. We are interested in defining which elements of the …
Regulation of Mec1 kinase activity by the SWI/SNF chromatin remodeling complex
P Kapoor, Y Bao, J Xiao, J Luo, J Shen… - Genes & …, 2015 - genesdev.cshlp.org
ATP-dependent chromatin remodeling complexes alter chromatin structure through
interactions with chromatin substrates such as DNA, histones, and nucleosomes. However …
interactions with chromatin substrates such as DNA, histones, and nucleosomes. However …
Structure of nucleosome-bound human PBAF complex
L Wang, J Yu, Z Yu, Q Wang, W Li, Y Ren… - Nature …, 2022 - nature.com
BAF and PBAF are mammalian SWI/SNF family chromatin remodeling complexes that
possess multiple histone/DNA-binding subunits and create nucleosome-depleted/free …
possess multiple histone/DNA-binding subunits and create nucleosome-depleted/free …
Actin-related proteins regulate the RSC chromatin remodeler by weakening intramolecular interactions of the Sth1 ATPase
The catalytic subunits of SWI/SNF-family and INO80-family chromatin remodelers bind actin
and actin-related proteins (Arps) through an N-terminal helicase/SANT-associated (HSA) …
and actin-related proteins (Arps) through an N-terminal helicase/SANT-associated (HSA) …
The AT-hook is an evolutionarily conserved auto-regulatory domain of SWI/SNF required for cell lineage priming
D Saha, S Hailu, A Hada, J Lee, J Luo… - Nature …, 2023 - nature.com
Abstract The SWI/SNF ATP-dependent chromatin remodeler is a master regulator of the
epigenome, controlling pluripotency and differentiation. Towards the C-terminus of the …
epigenome, controlling pluripotency and differentiation. Towards the C-terminus of the …
Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A. Z by SWR1C
The yeast SWR1C chromatin remodeling enzyme catalyzes the ATP-dependent exchange
of nucleosomal histone H2A for the histone variant H2A. Z, a key variant involved in a …
of nucleosomal histone H2A for the histone variant H2A. Z, a key variant involved in a …
The role of ATP-dependent chromatin remodeling complexes in regulation of genetic processes
MY Mazina, NE Vorobyeva - Russian Journal of Genetics, 2016 - Springer
Compaction of the genomic DNA into the chromatin structure reduces the accessibility of
DNAbinding protein sites and complicates the realization of replication and transcription. In …
DNAbinding protein sites and complicates the realization of replication and transcription. In …
Feed-forward regulation of phagocytosis by Entamoeba histolytica
A Sateriale, A Vaithilingam, L Donnelly… - Infection and …, 2012 - Am Soc Microbiol
The parasitic protozoan Entamoeba histolytica is aptly named for its capacity to destroy host
tissue. When E. histolytica trophozoites invade the lamina propria of a host colon …
tissue. When E. histolytica trophozoites invade the lamina propria of a host colon …