Down-regulation of histamine-induced endothelial cell activation as potential anti-atherosclerotic activity of peptides from Spirulina maxima

TS Vo, SK Kim - European Journal of Pharmaceutical Sciences, 2013 - Elsevier
Histamine, a potent inflammatory mediator, has been known to cause the pathogenesis of
atherosclerosis. In this sense, two bioactive peptides P1 (LDAVNR; 686 Da) and P2 …

From folk medicine to functional food: a review on the bioactive components and pharmacological properties of citrus peels

AO Ademosun, G Oboh, TA Olasehinde… - Oriental Pharmacy and …, 2018 - Springer
Citrus peels, which are an environmental menace in many developing countries have been
in use in folk medicine for the management of some degenerative conditions, though there …

[HTML][HTML] Pomegranate: A promising avenue against the most common chronic diseases and their associated risk factors

A Lavoro, L Falzone, G Gattuso… - International …, 2021 - spandidos-publications.com
Pomegranate is an important source of several bioactive compounds with beneficial
properties. As widely described in the literature, pomegranate can be considered as a …

[HTML][HTML] Current disease-targets for oleocanthal as promising natural therapeutic agent

A Segura-Carretero, JA Curiel - International Journal of Molecular …, 2018 - mdpi.com
The broad number of health benefits which can be obtained from the long-term consumption
of olive oil are attributed mainly to its phenolic fraction. Many olive oil phenolics have been …

A single serving of blueberry (V. corymbosum) modulates peripheral arterial dysfunction induced by acute cigarette smoking in young volunteers: A randomized …

C Del Bo, M Porrini, D Fracassetti, J Campolo… - Food & function, 2014 - pubs.rsc.org
Cigarette smoking causes oxidative stress, hypertension and endothelial dysfunction.
Polyphenol-rich foods may prevent these conditions. We investigated the effect of a single …

[HTML][HTML] Revealing and predicting the relationship between the molecular structure and antioxidant activity of flavonoids

Y Tao, H Zhang, Y Wang - Lwt, 2023 - Elsevier
Flavonoids have potential antioxidant activity and commercial value. Exploration of the
relationship between the properties of flavonoids and their molecular structure provides the …

[HTML][HTML] Combinatorial selection of molecular conformations and supramolecular synthons in quercetin cocrystal landscapes: a route to ternary solids

R Dubey, GR Desiraju - IUCrJ, 2015 - scripts.iucr.org
The crystallization of 28 binary and ternary cocrystals of quercetin with dibasic coformers is
analyzed in terms of a combinatorial selection from a solution of preferred molecular …

Cocoa, blood pressure, and cardiovascular health

C Ferri, G Desideri, L Ferri, I Proietti… - Journal of agricultural …, 2015 - ACS Publications
High blood pressure is an important risk factor for cardiovascular disease and
cardiovascular events worldwide. Clinical and epidemiological studies suggest that cocoa …

Chronic and acute effects of cocoa products intake on arterial stiffness and platelet count and function: A systematic review and dose-response Meta-analysis of …

B Jafari Azad, E Daneshzad, AP Meysamie… - Critical reviews in …, 2021 - Taylor & Francis
The findings of trials investigating the effect of cocoa products consumption on vascular
stiffness and platelet are controversial. The aim of this study is to summarize the findings on …

Inhibition of UGT1A1 by natural and synthetic flavonoids

XY Liu, X Lv, P Wang, CZ Ai, QH Zhou, M Finel… - International journal of …, 2019 - Elsevier
Flavonoids are widely distributed phytochemicals in vegetables, fruits and medicinal plants.
Recent studies demonstrate that some natural flavonoids are potent inhibitors of the human …