Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Novel agents addressing non-amyloid, non-tau targets in Alzheimer's Disease (AD)
comprise 70% of the AD drug development pipeline of agents currently in clinical trials. Most …

Epigallocatechin 3-gallate (EGCG), an abundant polyphenolic component derived from
green tea extract, possesses versatile bioactivities that can combat many diseases. During …

Parkinson's disease (PD) as a prevalent neurodegenerative condition impairs motor function
and is caused by the progressive deterioration of nigrostriatal dopaminergic (DAergic) …

Carbon monoxide (CO) has been firmly established as an endogenous signaling molecule
with a variety of pathophysiological and pharmacological functions, including …

Parkinson's disease is a neurodegenerative disease whose progression and clinical
characteristics have a close bidirectional and multilevel relationship with the process of …

Fibrosis refers to excessive build‐up of scar tissue and extracellular matrix components in
different organs. In recent years, it has been revealed that different cytokines and …

The increasing life expectancy has led to a higher incidence of age-related
neurodegenerative conditions. Within this framework, neuroinflammation emerges as a …

Neurodegenerative diseases (ND) include a wide range of conditions that result from
progressive damage to the neurons. Alzheimer's disease (AD) is one of the most common …

Abstract Ethnopharmacological relevance Fructus Gardeniae, with the effects of discharging
fire, eliminating vexation, reducing fever and causing diuresis, and cooling blood to remove …