[HTML][HTML] Polygenic risk scores in psychiatry: Will they be useful for clinicians?

JM Fullerton, JI Nurnberger - F1000Research, 2019 - ncbi.nlm.nih.gov
Major psychiatric disorders are heritable but they are genetically complex. This means that,
with certain exceptions, single gene markers will not be helpful for diagnosis. However, we …

[HTML][HTML] Psychiatry in the digital age: A blessing or a curse?

CB Roth, A Papassotiropoulos, AB Brühl… - International journal of …, 2021 - mdpi.com
Social distancing and the shortage of healthcare professionals during the COVID-19
pandemic, the impact of population aging on the healthcare system, as well as the rapid …

Targeted sequencing of the LRRTM gene family in suicide attempters with bipolar disorder

RD Reichman, SC Gaynor, ET Monson… - American Journal of …, 2020 - Wiley Online Library
Glutamatergic signaling is the primary excitatory neurotransmission pathway in the brain,
and its relationship to neuropsychiatric disorders is of considerable interest. Our previous …

[HTML][HTML] Polygenic predisposition, sleep duration, and depression: evidence from a prospective population-based cohort

OS Hamilton, A Steptoe, O Ajnakina - Translational Psychiatry, 2023 - nature.com
Suboptimal sleep durations and depression frequently cooccur. Short-sleep and long-sleep
are commonly thought of as symptoms of depression, but a growing literature suggests that …

The unmet needs for major depressive disorder

R McIntyre, H Gill - New directions in psychiatry, 2020 - Springer
Abstract Major Depressive Disorder (MDD) is a common brain-based disorder that is a major
cause of morbidity and mortality around the world. Moreover, it is highly comorbid with a …

Environmental, genetic and epigenetic contributors to the risk of bipolar disorder

S Hesam Shariati - 2022 - unsworks.unsw.edu.au
Bipolar disorder (BD) is a complex mental illness for which both environmental and
biological (genetic and epigenetic) factors play an aetiological role. This thesis aimed to find …

Identifying Potential Causal Risk Factors for Self-Harm: A Polygenic Risk Scoring and Mendelian Randomisation Approach

KX Lim, F Rijsdijk, SP Hagenaars, A Socrates, SW Choi… - BioRxiv, 2019 - biorxiv.org
Background Multiple individual vulnerabilities and traits are phenotypically associated with
suicidal and non-suicidal self-harm. However, associations between these risk factors and …

[引用][C] Janice Fullerton