Objectives The aim was to determine the accuracy of cell‐free DNA testing (cfDNA) for
detecting sex chromosome aneuploidies (SCA) in singleton pregnancies. Methods A …

Non‐invasive prenatal testing (NIPT) has been widely used to screen for common
aneuploidies since 2011. While NIPT is highly sensitive and specific, false positive results …

Background Due to educational, social and economic reasons, more and more women are
delaying childbirth. However, advanced maternal age is associated with several adverse …

The global liquid biopsy industry is expected to exceed $ US5 billion by 2023. One
application of liquid biopsy technology is the diagnosis of disease using biomarkers found in …

Difficult ethical issues arise for patients and professionals in medical genetics, and often
relate to the patient's family or their social context. Tackling these issues requires sensitivity …

Noninvasive prenatal DNA testing is the vanguard of genomic medicine. In only four years,
this screening test has revolutionized prenatal care globally and opened up new prospects …

Circulating cell-free DNA (cfDNA) and RNA (cfRNA) hold enormous potential as a new class
of biomarkers for the development of noninvasive liquid biopsies in many diseases and …

Non-invasive prenatal testing (NIPT) is at the forefront of prenatal screening. Current uses
for NIPT include fetal sex determination and screening for chromosomal disorders such as …

The expanding use of genomic technologies encompasses all phases of life, from the
embryo to the elderly, and even the posthumous phase. In this paper, we present the …

Background The next generation sequencing (NGS) based non-invasive prenatal test (NIPT)
has outplayed the traditional serum biochemical tests (SBT) in screen of fetal aneuploidies …