Helicobacter pylori infection and antibiotic resistance — from biology to clinical implications

E Tshibangu-Kabamba, Y Yamaoka - Nature Reviews Gastroenterology …, 2021 - nature.com
Helicobacter pylori is a major human pathogen for which increasing antibiotic resistance
constitutes a serious threat to human health. Molecular mechanisms underlying this …

the global emergence of Helicobacter pylori antibiotic resistance

I Thung, H Aramin, V Vavinskaya… - Alimentary …, 2016 - Wiley Online Library
Background Helicobacter pylori is one of the most prevalent global pathogens and can lead
to gastrointestinal disease including peptic ulcers, gastric marginal zone lymphoma and …

Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

SS Dominy, C Lynch, F Ermini, M Benedyk… - Science …, 2019 - science.org
Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in
the brain of Alzheimer's disease patients. Toxic proteases from the bacterium called …

Helicobacter pylori infection, its laboratory diagnosis, and antimicrobial resistance: a perspective of clinical relevance

S Ansari, Y Yamaoka - Clinical microbiology reviews, 2022 - Am Soc Microbiol
Despite the recent decrease in overall prevalence of Helicobacter pylori infection, morbidity
and mortality rates associated with gastric cancer remain high. The antimicrobial resistance …

[HTML][HTML] Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing

D Pohl, PM Keller, V Bordier… - World journal of …, 2019 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is highly prevalent in the human population and may
lead to severe gastrointestinal pathology including gastric and duodenal ulcers, mucosa …

Helicobacter pylori Detection and Antimicrobial Susceptibility Testing

F Mégraud, P Lehours - Clinical microbiology reviews, 2007 - Am Soc Microbiol
The discovery of Helicobacter pylori in 1982 was the starting point of a revolution concerning
the concepts and management of gastroduodenal diseases. It is now well accepted that the …

Experimental evidence for the age dependence of tau protein spread in the brain

S Wegmann, RE Bennett, L Delorme, AB Robbins… - Science …, 2019 - science.org
The incidence of Alzheimer's disease (AD), which is characterized by progressive cognitive
decline that correlates with the spread of tau protein aggregation in the cortical mantle, is …

[HTML][HTML] New concepts of resistance in the treatment of Helicobacter pylori infections

DY Graham, A Shiotani - Nature clinical practice Gastroenterology & …, 2008 - nature.com
The prevalence of antimicrobial drug resistance is now so high that all patients infected with
Helicobacter pylori should be considered as having resistant infections. Ideally, therapy …

Helicobacter pylori and antimicrobial resistance: molecular mechanisms and clinical implications

MM Gerrits, AHM van Vliet, EJ Kuipers… - The Lancet infectious …, 2006 - thelancet.com
Helicobacter pylori is an important human pathogen that colonises the stomach of about half
of the world's population. The bacterium has now been accepted as the causative agent of …

Optimal therapy for Helicobacter pylori infections

E Rimbara, LA Fischbach, DY Graham - … reviews Gastroenterology & …, 2011 - nature.com
Although Helicobacter pylori infection is both a common and a serious bacterial infection,
antimicrobial therapies have rarely been optimized, are prescribed empirically, and provide …