Chronic pain is a common problem, with more than one-fifth of adult Americans reporting
pain daily or on most days. It adversely affects the quality of life and imposes substantial …

Beyond the core features of Alzheimer's disease (AD) pathology, ie amyloid pathology, tau-
related neurodegeneration and microglia response, multiple other molecular alterations and …

Most patients with Alzheimer's disease (AD) develop neuropsychiatric symptoms (NPS)
alongside cognitive decline, and apathy is one of the most common symptoms. Few …

Artificial Intelligence (AI), which is the general term used to describe technology that
simulates human cognition [1], has taken on a prominent role in twenty-first-century clinical …

For over a century, brain research narrative has mainly centered on neuron cells.
Accordingly, most neurodegenerative studies focus on neuronal dysfunction and their …

Background Rare diseases are estimated to affect more than one in ten Americans.
However, most patients with a rare disease face significant emotional, physical, and social …

Chronic pain is a common problem, with more than one-fifth of adult Americans reporting
pain daily or on most days. It adversely affects quality of life and imposes substantial …

Neurodegenerative diseases are characterized by the progressive loss of neurons,
synapses, dendrites, and myelin in the central and/or peripheral nervous system. Actual …

Neuropsychiatric and substance use disorders (NPSUDs) have a complex etiology that
includes environmental and polygenic risk factors with significant cross-trait genetic …

Abstract Neuropsychiatric symptoms (NPSs) in Alzheimer's disease (AD) constitute
multifaceted behavioral manifestations that reflect processes of emotional regulation …