Reactive oxygen species, toxicity, oxidative stress, and antioxidants: Chronic diseases and aging

K Jomova, R Raptova, SY Alomar, SH Alwasel… - Archives of …, 2023 - Springer
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

The genetic basis of major depressive disorder

J Flint - Molecular psychiatry, 2023 - nature.com
The genetic dissection of major depressive disorder (MDD) ranks as one of the success
stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …

[HTML][HTML] Prevalence of depression symptoms in US adults before and during the COVID-19 pandemic

CK Ettman, SM Abdalla, GH Cohen… - JAMA network …, 2020 - jamanetwork.com
Importance The coronavirus disease 2019 (COVID-19) pandemic and the policies to contain
it have been a near ubiquitous exposure in the US with unknown effects on depression …

The impact of stress on students in secondary school and higher education

MC Pascoe, SE Hetrick, AG Parker - International journal of …, 2020 - Taylor & Francis
Students in secondary and tertiary education settings face a wide range of ongoing stressors
related to academic demands. Previous research indicates that academic-related stress can …

The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders

ETC Lippard, CB Nemeroff - American journal of psychiatry, 2020 - Am Psychiatric Assoc
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Animal models of major depression: drawbacks and challenges

B Planchez, A Surget, C Belzung - Journal of Neural Transmission, 2019 - Springer
Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …

[HTML][HTML] Canalization and plasticity in psychopathology

RL Carhart-Harris, S Chandaria, DE Erritzoe… - …, 2023 - Elsevier
This theoretical article revives a classical bridging construct, canalization, to describe a new
model of a general factor of psychopathology. To achieve this, we have distinguished …

Associations of risk perception of COVID-19 with emotion and mental health during the pandemic

Q Han, B Zheng, M Agostini, JJ Bélanger… - Journal of affective …, 2021 - Elsevier
Background Although there are increasing concerns on mental health consequences of the
COVID-19 pandemic, no large-scale population-based studies have examined the …

Oxidative stress and the central nervous system

S Salim - Journal of Pharmacology and Experimental …, 2017 - ASPET
Biochemical integrity of the brain is vital for normal functioning of the central nervous system
(CNS). One of the factors contributing to cerebral biochemical impairment is a chemical …

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

N Cai, JA Revez, MJ Adams, TFM Andlauer, G Breen… - Nature …, 2020 - nature.com
Minimal phenotyping refers to the reliance on the use of a small number of self-reported
items for disease case identification, increasingly used in genome-wide association studies …