Diabetes is associated with vascular injury and the onset of macrovascular complications.
Advanced glycation endproducts (AGEs) and the AGE precursor methylglyoxal (MGO) have …

Diabetes mellitus is a major public health issue that affected 537 million people worldwide in
2021, a number that is only expected to increase in the upcoming decade. Diabetes is a …

Vascular endothelial injury in diabetes mellitus (DM) is the major cause of vascular disease,
which is closely related to the occurrence and development of a series of vascular …

Methylglyoxal (MGO) is the major compound belonging to reactive carbonyl species (RCS)
responsible for the generation of advanced glycation end products (AGEs). Its upregulation …

Adipose-derived stem cells (ASCs) have been used as a therapeutic intervention for
peripheral artery disease (PAD) in clinical trials. To further explore the therapeutic …

Hyperglycemia in pregnancy (HIP) is linked to fetoplacental endothelial dysfunction, which
might be a result of hyperglycemia. Hyperglycemia is associated with cell senescence; …

Resistance exercise provides significant benefits to skeletal muscle, including hypertrophy
and metabolic enhancements, supporting overall health and disease management …

Background Hypoxia in ischemic disease impairs Ca2+ homeostasis and may promote
angiogenesis. The therapeutic efficacy of mesenchymal stromal cells (MSCs) in peripheral …

Although femoral artery dysfunctions, including aberrant vascular reactivity to vasoactive
substances, are common in many chronic disorders, such as diabetes and hypertension …