Therapeutic drug monitoring (TDM) of conventional cytotoxic chemotherapies is strongly
supported yet poorly implemented in daily practice in hospitals. Analytical methods for the …

Background: Compared with anti-infective drugs, immunosuppressants and other fields, the
application of therapeutic drug monitoring (TDM) in oncology is somewhat limited. Objective …

Background Acne vulgaris is a widespread chronic inflammatory dermatological condition.
The precise molecular and genetic mechanisms of its pathogenesis remain incompletely …

The existence of the blood-brain barrier (BBB) and blood-brain tumor barrier (BBTB) greatly
limits the application of chemotherapy in glioma. To address this challenge, an optimal drug …

In the era of precision medicine, there is increasing evidence that conventional cytotoxic
agents may be suitable candidates for therapeutic drug monitoring (TDM)-guided drug …

Despite great efforts to develop new therapeutic strategies to combat melanoma, the
prognosis remains rather poor. Artesunate (ART) is an antimalarial drug displaying anti …

Cancer stands as a leading cause of global mortality, with chemotherapy being a pivotal
treatment approach, either alone or in conjunction with other therapies. The primary goal of …

Most traditional cytotoxic drugs are characterized by steep dose–response relationships and
narrow therapeutic windows. Their inter-individual pharmacokinetic (PK) variability is often …

Background Busulfan is widely used in conditioning regimens to prepare patients for
hematopoietic stem cell transplantation. Therapeutic drug monitoring (TDM) is critical due to …

Over the last three to four decades, Therapeutic Drug Monitoring (TDM) has shaped itself as
therapeutic drug management, an integral component of precision medicine. The practice of …