Abstract Type I interferon (IFN-I) plays crucial roles in the regulation of inflammation and it is
associated with various inflammatory diseases including systemic lupus erythematosus …

Catastrophic antiphospholipid syndrome (CAPS) is a rare and life-threatening condition
characterized by the persistence of antiphospholipid antibodies and occurrence of multiple …

The Helios protein (encoded by the IKZF2 gene) is a member of the Ikaros transcription
family and it has recently been proposed as a promising biomarker for systemic lupus …

V-domain immunoglobulin suppressor of T-cell activation (VISTA), an important negative
checkpoint protein, participates in immunoregulation. Systemic lupus erythematosus (SLE) …

Background Although fish oil has been considered to have an anti-inflammatory effect and
has been proven to play a beneficial role in the incidence of numerous diseases, the …

Systemic autoimmune diseases (SAIDs), such as systemic lupus erythematosus (SLE),
systemic sclerosis (SSc) and rheumatoid arthritis (RA), are fully related to the unregulated …

ABSTRACT Mesenchymal Stem Cells (MSCs) are of interest in the clinic because of their
immunomodulation capabilities, capacity to act upstream of inflammation, and ability to …

Systemic lupus erythematosus (SLE), a chronic autoimmune disease, is marked by impaired
immune tolerance and heightened activity in both innate and adaptive immune systems …

Abstract Interferon regulatory factor 4 (IRF4) is a member of IRF family of transcription factors
which mainly regulates the transcription of IFN. IRF4 is restrictively expressed in immune …

State of the art: the treatment of systemic lupus erythematosus Page 1 ACI 240411
CURRENT OPINION State of the art: the treatment of systemic lupus erythematosus Giulia …