Circulating microRNAs as clinically useful biomarkers for Type 2 Diabetes Mellitus: miRNomics from bench to bedside

GE Grieco, ZM Besharat, G Licata, D Fignani… - Translational …, 2022 - Elsevier
Type 2 diabetes (T2D), a chronic metabolic disease, has attained the status of a global
epidemic with steadily increasing incidence worldwide. Improved diagnosis, stratification …

[HTML][HTML] The necessity of incorporating non-genetic risk factors into polygenic risk score models

S van Dam, P Folkertsma, J Castela Forte… - Scientific Reports, 2023 - nature.com
The growing public interest in genetic risk scores for various health conditions can be
harnessed to inspire preventive health action. However, current commercially available …

[HTML][HTML] Phenotypic and Genetic Factors Associated with Absence of Cardiomyopathy Symptoms in PLN: c. 40_42delAGA Carriers

EA Lopera-Maya, S Li, R de Brouwer, IM Nolte… - Journal of …, 2023 - Springer
Abstract The c. 40_42delAGA variant in the phospholamban gene (PLN) has been
associated with dilated and arrhythmogenic cardiomyopathy, with up to 70% of carriers …

[HTML][HTML] MicroRNA circolanti come biomarcatori per il diabete mellito di tipo 2: avanzamenti e prospettive future

GE Grieco, D Fignani, F Dotta, G Sebastiani - L'Endocrinologo, 2022 - Springer
Il diabete mellito di tipo 2 (DMT2) è una malattia metabolica cronica eterogenea in costante
aumento. In questa rassegna, al fine di identificare un gruppo di microRNA (miRNA) con …