Chronic kidney disease (CKD) is a devastating condition that is reaching epidemic levels
owing to the increasing prevalence of diabetes mellitus, hypertension and obesity, as well …

microRNAs (miRNAs) are small, non-coding nucleotides that regulate diverse biological
processes. Altered microRNA biosynthesis or regulation contributes to pathological …

As a self-degradative mechanism, macroautophagy/autophagy has a role in the
maintenance of energy homeostasis during critical periods in the development of cells. It …

Autophagy is a cellular homeostatic program for the turnover of cellular organelles and
proteins, in which double-membraned vesicles (autophagosomes) sequester cytoplasmic …

Over almost 140 years since their identification, the knowledge about macrophages has
unbelievably evolved. The'big eaters' from being thought of as simple phagocytic cells have …

Autophagy is a ubiquitous intracellular cytoprotective quality control program that maintains
cellular homeostasis by recycling superfluous cytoplasmic components (lipid droplets …

Context Baicalin, a flavonoid extracted from radix scutellariae, possesses various
pharmacological effects, including protective effects on renal interstitial fibrosis (RIF), but its …

Autophagy is a homeostatic process designed to eliminate dysfunctional and aging
organelles and misfolded proteins through a well-concerted pathway, starting with forming a …

OBJECTIVE: To observe the efficacy of Danggui Buxue decoction (当归补血汤, DBD) on
diabetic nephropathy-induced renal fibrosis in rats, and to study the possible mechanism …

Current literature has indicated that Peyronie's disease (PD) could be initiated by
microtrauma and the subsequent inflammation episodes that follow. PD could be sorted into …