Cost of introducing and delivering malaria vaccine (RTS, S/AS01E) in areas of seasonal malaria transmission, Mali and Burkina Faso
H Diawara, FY Bocoum, A Dicko, A Levin, C Lee… - BMJ Global …, 2023 - gh.bmj.com
Background The WHO recommends use of the RTS, S/AS01E (RTS, S) malaria vaccine for
young children living in areas of moderate to high Plasmodium falciparum malaria …
young children living in areas of moderate to high Plasmodium falciparum malaria …
[HTML][HTML] Perennial malaria chemoprevention with and without malaria vaccination to reduce malaria burden in young children: a modelling analysis
Background A recent WHO recommendation for perennial malaria chemoprevention (PMC)
encourages countries to adapt dose timing and number to local conditions. However …
encourages countries to adapt dose timing and number to local conditions. However …
Economic impact of introducing the RTS, S malaria vaccine: cost-effectiveness and budget impact analysis in 41 countries
C Sauboin, LA Van Bellinghen… - MDM Policy & …, 2019 - journals.sagepub.com
Background. Malaria is a major public health burden in sub-Saharan Africa. This study
estimated the cost-effectiveness and budget impact of adding four-dose malaria vaccination …
estimated the cost-effectiveness and budget impact of adding four-dose malaria vaccination …
[HTML][HTML] RTS, S/AS01 malaria vaccine efficacy is not modified by seasonal precipitation: results from a phase 3 randomized controlled trial in Malawi
Abstract The World Health Organization has selected Malawi as one of three sites to pilot the
roll-out of RTS, S/AS01 in phase 4 trials. As policy discussions for the expanded use of RTS …
roll-out of RTS, S/AS01 in phase 4 trials. As policy discussions for the expanded use of RTS …
[HTML][HTML] Cost-effectiveness and public health impact of RTS, S/AS01 E malaria vaccine in Malawi, using a Markov static model
Background: The RTS, S/AS01 E malaria vaccine is being assessed in Malawi, Ghana and
Kenya as part of a large-scale pilot implementation programme. Even if impactful, its …
Kenya as part of a large-scale pilot implementation programme. Even if impactful, its …
[HTML][HTML] Analysis of the potential for a malaria vaccine to reduce gaps in malaria intervention coverage
Abstract Background The RTS, S/AS01 malaria vaccine is currently being evaluated in a
cluster-randomized pilot implementation programme in three African countries. This study …
cluster-randomized pilot implementation programme in three African countries. This study …
Leveraging mathematical models of disease dynamics and machine learning to improve development of novel malaria interventions
M Golumbeanu, GJ Yang, F Camponovo… - Infectious Diseases of …, 2022 - mednexus.org
Background: Substantial research is underway to develop next-generation interventions that
address current malaria control challenges. As there is limited testing in their early …
address current malaria control challenges. As there is limited testing in their early …
Malaria modeling in the era of eradication
Mathematical models provide the essential basis of rational research and development
strategies in malaria, informing the choice of which technologies to target, which deployment …
strategies in malaria, informing the choice of which technologies to target, which deployment …
[HTML][HTML] Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of …
F Camponovo, CF Ockenhouse, C Lee… - BMC infectious …, 2019 - Springer
Background The only licensed malaria vaccine, RTS, S/AS01, has been developed for
morbidity-control in young children. The potential impact on transmission of deploying such …
morbidity-control in young children. The potential impact on transmission of deploying such …
Implementation of RTS, S/AS01 malaria vaccine—the need for further evidence
In 2015, an estimated 438,000 people died from malaria. 1 The overwhelming majority of
these deaths occurred in young African children who were infected with Plasmodium …
these deaths occurred in young African children who were infected with Plasmodium …