Reelin was originally identified as a regulator of neuronal migration and synaptic function,
but its non-neuronal functions have received far less attention. Reelin participates in organ …

The number of patients with type 2 diabetes mellitus (T2DM), which is mainly characterized
by insulin resistance and insulin secretion deficiency, has been soaring in recent years …

Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors
upon the binding of physiological or pharmacological ligands and heterodimerization with …

Peroxisome proliferator‐activated receptors (PPARs) are transcription factors belonging to
the nuclear receptor family. There are three subtypes of PPARs, including PPAR‐α, PPAR …

Coronavirus disease 2019 (COVID-19) is a severe respiratory disease caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects the lower …

Pulmonary fibrosis is a chronic, fibrotic lung disease affecting 3 million people worldwide.
The ACE2/Ang-(1–7)/MasR axis is of interest in pulmonary fibrosis due to evidence of its anti …

Obesity and breast cancer are two major health issues that could be categorized as sincere
threats to human health. In the last few decades, the relationship between obesity and …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease that lacks
effective treatment modalities. Once patients are diagnosed with IPF, their median survival is …

Fibrosis, which causes structural hardening and functional degeneration in various organs,
is characterized by the excessive production and accumulation of connective tissue …

Objective: Sarcopenia or frailty is common among patients with chronic kidney disease
(CKD). The protein-bound uremic toxin indoxyl sulfate (IS) is associated with frailty. IS …