Background Despite advances in antenatal and neonatal care, preterm birth remains a
leading cause of neurological disabilities in children. Infants born prematurely, particularly …

Developmental dyslexia runs in families, and twin studies have confirmed that there is a
substantial genetic contribution to poor reading. The way in which discoveries in molecular …

General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …

Behavioral genetics and cultural evolution have both revolutionized our understanding of
human behavior–largely independent of each other. Here, we reconcile these two fields …

Pedigree-based analyses of intelligence have reported that genetic differences account for
50–80% of the phenotypic variation. For personality traits these effects are smaller, with 34 …

Alzheimer's disease (AD) is a devastating neurological disorder characterized by changes in
cell-type proportions and consequently marked alterations of the transcriptome. Here we use …

Objective Co-occurrence of mental disorders is commonly observed, but the etiology
underlying this observation is poorly understood. Studies in adolescents and adults have …

Schizophrenia is characterized by neuropsychological deficits across many cognitive
domains. Cognitive phenotypes with high heritability and genetic overlap with schizophrenia …

We explore the relation between age at menarche, parity and age at natural menopause
with 249 metabolic traits in over 65,000 UK Biobank women using multivariable regression …

General cognitive (intelligence) function is substantially heritable, and is a major
determinant of economic and health-related life outcomes. Cognitive impairments and …