Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) resulting in dopamine …

Neurodegenerative disorders (NDs) have become a serious health problem worldwide due
to the rapid increase in the number of people that are affected and the constantly aging …

Nasal drug delivery has been employed as an alternate and convenient route for the
systemic availability of pharmaceuticals, particularly for potent therapeutics. This is owing to …

This review aims to cement three hot topics in drug delivery:(a) the pre-formulation of new
products intended for nose-to-brain delivery;(b) the development of nasal casts for studying …

Indium tin oxide (ITO) is a semiconductor nanomaterial with broad application in liquid
crystal displays, solar cells, and electrochemical immune sensors. It is worth noting that, with …

Introduction This work aimed to develop chitosan-coated cubosomal nanoparticles intended
for nose-to-brain delivery of paliperidone palmitate. They were compared with standard and …

Drug delivery via the pulmonary route is a cornerstone in the pharmaceutical sector as an
alternative to oral and parenteral administration. Nebulizer inhalation treatment offers …

Nose-to-brain delivery is a promising way to improve the treatment of central nervous system
disorders, as it allows the bypassing of the blood–brain barrier. However, it is still largely …

Objectives To compare the deposition patterns within the nasal cavity between the bi‐
directional and unilateral nasal delivery systems. And to summarize the clinical application …

Nose-to-brain delivery is a promising way to reach the central nervous system with
therapeutic drugs. However, the location of the olfactory region at the top of the nasal cavity …