The effects of acute psychological stress on circulating and stimulated inflammatory markers: a systematic review and meta-analysis

AL Marsland, C Walsh, K Lockwood… - Brain, behavior, and …, 2017 - Elsevier
Inflammatory reactivity to acute laboratory stress is thought to reflect individual differences in
responsivity to environmental stressors and may confer future health risk. To characterize …

[HTML][HTML] Research progress in the epidemiology of HIV/AIDS in China

N He - China CDC weekly, 2021 - ncbi.nlm.nih.gov
After thirty-two years since the first domestic outbreak of human immunodeficiency virus
(HIV)/acquired immune deficiency syndrome (AIDS) among injection drug users (IDUs) and …

Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases

C Sturgeon, A Fasano - Tissue barriers, 2016 - Taylor & Francis
Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium
with its barrier function is in charge of a tightly controlled antigen trafficking from the …

Cross-sectional Comparison of the Prevalence of Age-Associated Comorbidities and Their Risk Factors Between HIV-Infected and Uninfected Individuals: The AGEh …

J Schouten, FW Wit, IG Stolte… - Clinical Infectious …, 2014 - academic.oup.com
Age-associated comorbidities (cardiovascular and renal disease) were more prevalent
among HIV-positive compared with HIV-uninfected patients. Comorbidity was associated …

HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased …

S Serrano-Villar, T Sainz, SA Lee, PW Hunt… - PLoS …, 2014 - journals.plos.org
A low CD4/CD8 ratio in elderly HIV-uninfected adults is associated with increased morbidity
and mortality. A subset of HIV-infected adults receiving effective antiretroviral therapy (ART) …

Clonal hematopoiesis, somatic mosaicism, and age-associated disease

MA Evans, K Walsh - Physiological Reviews, 2023 - journals.physiology.org
Somatic mosaicism, the occurrence of multiple genetically distinct cell clones within the
same tissue, is an evitable consequence of human aging. The hematopoietic system is no …

Association between HIV infection and the risk of heart failure with reduced ejection fraction and preserved ejection fraction in the antiretroviral therapy era: results …

MS Freiberg, CCH Chang, M Skanderson… - JAMA …, 2017 - jamanetwork.com
Importance With improved survival, heart failure (HF) has become a major complication for
individuals with human immunodeficiency virus (HIV) infection. It is unclear if this risk …

HIV infection

SG Deeks, J Overbaugh, A Phillips… - Nature reviews Disease …, 2015 - nature.com
More than 75 million people worldwide have been infected with human immunodeficiency
virus (HIV), and there are now approximately 37 million individuals living with the infection …

[HTML][HTML] Methylome-wide analysis of chronic HIV infection reveals five-year increase in biological age and epigenetic targeting of HLA

AM Gross, PA Jaeger, JF Kreisberg, K Licon… - Molecular cell, 2016 - cell.com
HIV-infected individuals are living longer on antiretroviral therapy, but many patients display
signs that in some ways resemble premature aging. To investigate and quantify the impact of …

Inflammation, ageing and chronic disease

G Pawelec, D Goldeck, E Derhovanessian - Current opinion in immunology, 2014 - Elsevier
Highlights•Elderly people commonly show signs of low level systemic inflammation.•Causes
include presence of senescent cells, chronic infections and obesity.•Systemic inflammation …