Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …

Foreword This Journal feature begins with a case vignette that includes a therapeutic
recommendation. A discussion of the clinical problem and the mechanism of benefit of this …

Background India has the highest burden of acute coronary syndromes in the world, yet little
is known about the treatments and outcomes of these diseases. We aimed to document the …

BACKGROUND: Among patients with ST-segment elevation myocardial infarction (STEMI),
rapid reperfusion is associated with improved mortality. As such, door-to-needle (D2N) and …

Following myocardial infarction, nonischemic myocyte death results in infarct expansion,
myocardial loss, and ventricular dysfunction. Here, we demonstrate that a specific …

BACKGROUND Prior research has documented the under‐representation in clinical trials of
older patients with cancer. In part of a larger study to test the magnitude of these barriers to …

Alleviating myocardial injury associated with ST elevation myocardial infarction is central to
improving the global burden of coronary heart disease. The chemokine stromal cell-derived …

Recent developments have provided a unique opportunity for the organization of regional
ST-elevation myocardial infarction (STEMI) receiving center (SRC) networks. Because …

Primary percutaneous coronary intervention (pPCI) is associated with improved prognosis in
patients with ST-segment elevation myocardial infarction (STEMI). However, no-reflow …

Background The use of metformin after acute myocardial infarction (AMI) has been
associated with reduced mortality in people with type 2 diabetes mellitus (T2DM). However …