Developing CAR-immune cell therapy against SARS-COV-2: Current status, challenges, and prospects
Y Chen, C Liu, Y Fang, W Chen, J Qiu, M Zhu… - Biochemical …, 2024 - Elsevier
Chimeric antigen receptor (CAR)-immune cell therapy has revolutionized the anti-tumor
field, achieving efficient and precise tumor clearance by directly guiding immune cell activity …
field, achieving efficient and precise tumor clearance by directly guiding immune cell activity …
Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA. 2.86, EG. 5.1, and JN. 1
Z Tong, J Tong, W Lei, Y Xie, Y Cui, G Jia, S Li… - Cell Reports, 2024 - cell.com
The game between therapeutic monoclonal antibodies (mAbs) and continuously emerging
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has favored the …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has favored the …
Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses
C Liu, S Xu, Y Zheng, Y Xie, K Xu, Y Chai, T Luo, L Dai… - Cell Reports, 2024 - cell.com
Nanoparticle vaccines displaying mosaic receptor-binding domains (RBDs) or spike (S) from
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or other sarbecoviruses are …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or other sarbecoviruses are …
Spike structures, receptor binding, and immune escape of recently circulating SARS-CoV-2 Omicron BA. 2.86, JN. 1, EG. 5, EG. 5.1, and HV. 1 sub-variants
L Li, K Shi, Y Gu, Z Xu, C Shu, D Li, J Sun, M Cong, X Li… - Structure, 2024 - cell.com
Summary The recently emerged BA. 2.86, JN. 1, EG. 5, EG. 5.1, and HV. 1 variants have a
growth advantage. In this study, we explore the structural bases of receptor binding and …
growth advantage. In this study, we explore the structural bases of receptor binding and …
[HTML][HTML] The binding and structural basis of fox ACE2 to RBDs from different sarbecoviruses
J Chen, J Sun, Z Xu, L Li, X Kang, C Luo, Q Wang… - Virologica Sinica, 2024 - Elsevier
Foxes are susceptible to SARS-CoV-2 in laboratory settings, and there have also been
reports of natural infections of both SARS-CoV and SARS-CoV-2 in foxes. In this study, we …
reports of natural infections of both SARS-CoV and SARS-CoV-2 in foxes. In this study, we …