Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Osteoarthritis (OA), a prevalent degenerative joint disease, affects a substantial global
population. Despite the elusive etiology of OA, recent investigations have implicated …

Severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is responsible for
coronavirus disease of 2019 (COVID‐19) that infected more than 760 million people …

Acute lung injury (ALI) is generally caused by severe respiratory infection and characterized
by overexuberant inflammatory responses and inefficient pathogens-containing, the two …

Introduction 'Insulin sensitizers' derived discoveries of the Takeda Company in 1970s.
Pioglitazone remains the best in class with beneficial pleiotropic pharmacology, although …

To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an
exhaustive survey of the cellular metabolic pathways modulated by SARS-CoV-2 infection …

HIV-associated lipodystrophy has been reported in people taking anti-retroviral therapy
(ART). Lipodystrophy can cause cardiovascular diseases, affecting the quality of life of HIV …

Fasting has been shown to affect the distri bution of leukocytes in the body, but the
underlying mechanisms are poorly under stood. A report in Immunityinvestigated the …

Itaconate has been well recognized as an anti-inflammatory metabolite that displays
therapeutic potential in multiple diseases, including inflammatory lung diseases. However …