Anti-depressant properties of crocin molecules in saffron

SA Siddiqui, A Ali Redha, ER Snoeck, S Singh… - Molecules, 2022 - mdpi.com
Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with
therapeutic effects. It has been described in pharmacopoeias to be variously acting …

Phytotherapy of mood disorders in the light of microbiota-gut-brain axis.

M Korczak, M Pilecki, S Granica, A Gorczynska… - Phytomedicine, 2023 - Elsevier
Background Clinical research in natural product-based psychopharmacology has revealed
a variety of promising herbal medicines that may provide benefit in the treatment of mild …

The effects of saffron (Crocus sativus L.) in conjunction with concurrent training on body composition, glycaemic status, and inflammatory markers in obese men with …

B Hooshmand Moghadam… - British Journal of …, 2022 - Wiley Online Library
Aims Chronic inflammation is one of the major challenges in the management of obesity and
type 2 diabetes mellitus (T2DM). Our primary aim was to assess the anti‐inflammatory …

Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr'InsideTM) Protect Neurons from Oxidative Stress: Consideration for …

F Wauquier, L Boutin-Wittrant, L Pourtau, D Gaudout… - Nutrients, 2022 - mdpi.com
Increases in oxidative stress have been reported to play a central role in the vulnerability to
depression, and antidepressant drugs may reduce increased oxidative stress in patients …

Current Knowledge of the Antidepressant Activity of Chemical Compounds from Crocus sativus L.

R Matraszek-Gawron, M Chwil, K Terlecki… - Pharmaceuticals, 2022 - mdpi.com
Psychotropic effect of Crocus sativus L.(family Iridaceae) biologically active chemical
compounds are quite well documented and they can therefore be used in addition to the …

The effect of saffron supplementation on blood pressure in adults: a systematic review and dose-response meta-analysis of randomized controlled trials

L Setayesh, D Ashtary-Larky, CCT Clark… - Nutrients, 2021 - mdpi.com
Background: The favorable influences of saffron supplementation on metabolic diseases
have previously been shown. We aimed to assess the effects of saffron supplementation on …

Fighting the consequences of the COVID-19 pandemic: mindfulness, exercise, and nutrition practices to reduce eating disorders and promote sustainability

S Baldassano, A Alioto, A Amato, C Rossi, G Messina… - Sustainability, 2023 - mdpi.com
Over the past two years, the world's population has been tested by the COVID-19 health
emergency. This has changed population habits worldwide by encouraging a sedentary …

Saffron carotenoids reversed the UCMS-induced depression and anxiety in rats: Behavioral and biochemical parameters, and hippocampal BDNF/ERK/CREB and …

S Mohammadi, M Naseri, N Faridi, P Zareie, L Zare… - Phytomedicine, 2023 - Elsevier
Background Depression is a debilitating condition that affects the mind and the individual's
body. The improving effects of saffron on depression and anxiety have long been discussed …

The effect of Crocus sativus L. (saffron) herbal tea on happiness in postmenopausal women: a randomized controlled trial

H Delam, Z Keshtkaran, N Shokrpour, A Eidi… - … Medicine and Therapies, 2023 - Springer
Background Evidence suggests that menopause can be associated with a variety of
negative psychological changes such as depression and anxiety, and improving the mental …

Gut Bacteria Regulate the Pathogenesis of Huntington's Disease in Drosophila Model

A Chongtham, JH Yoo, TM Chin… - Frontiers in …, 2022 - frontiersin.org
Changes in the composition of gut microbiota are implicated in the pathogenesis of several
neurodegenerative disorders. Here, we investigated whether gut bacteria affect the …