Epidemiologic studies have shown a reduced risk of developing Parkinson's disease (PD)
among cigarette smokers. Nicotine, as a key component in tobacco products, is thought as a …

Parkinson's disease (PD) is a common age-related neurodegenerative disorder, which may
be largely due to the mitochondrial dysfunction and impaired mitophagy. Thus, it is of great …

Astrocytes can protect neurons against oxidative stress and excitability-dependent
disorders, such as epilepsy. Valeriana officinalis has been used as anticonvulsant and can …

CRISPR is a simple and cost-efficient gene-editing technique that has become increasingly
popular over the last decades. Various CRISPR/Cas-based applications have been …

Abstract Background MPTP (1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine), original found
in synthetic heroin, causes Parkinson's disease (PD) in human through its metabolite MPP+ …

Every year, tens of millions of individuals worldwide are affected by neurodegenerative
illnesses, which are defined by the inevitable annihilation of non-specific surroundings brain …

Parkinson's disease (PD) is a complex, multifactorial neurodegenerative disease with a
prevalence of 1% over the age of 55. Neuropathological hallmarks of PD include the loss of …

Purpose Parkinson's disease (PD) is the second most common neurodegenerative disease
without cure or effective treatment. This study explores whether the yeast internal NADH …

There is an urgent unmet need in the Parkinson's disease community—advanced therapies
to modify the inevitable decline that occurs in those affected by this progressive …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder globally,
significantly affecting the quality of life of affected individuals. Systemic drug delivery to the …