The roles of lipids in SARS-CoV-2 viral replication and the host immune response
The significant morbidity and mortality associated with severe acute respiratory syndrome
coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play …
coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play …
Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the responsible agent for
the coronavirus disease 2019 (Covid-19), has its entry point through interaction with …
the coronavirus disease 2019 (Covid-19), has its entry point through interaction with …
[HTML][HTML] High levels of eicosanoids and docosanoids in the lungs of intubated COVID‐19 patients
Severe acute respiratory syndrome coronavirus 2 is responsible for coronavirus disease
2019 (COVID‐19). While COVID‐19 is often benign, a subset of patients develops severe …
2019 (COVID‐19). While COVID‐19 is often benign, a subset of patients develops severe …
Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-Siglec-8 antibody
S Gebremeskel, J Schanin, KM Coyle… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection represents a
global health crisis. Immune cell activation via pattern recognition receptors has been …
global health crisis. Immune cell activation via pattern recognition receptors has been …
Understanding the pathophysiological changes via untargeted metabolomics in COVID‐19 patients
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious respiratory disease caused
by a new strain of the coronavirus. There is limited data on the pathogenesis and the cellular …
by a new strain of the coronavirus. There is limited data on the pathogenesis and the cellular …
Host metabolic reprogramming in response to SARS-CoV-2 infection: A systems biology approach
Understanding the pathogenesis of SARS-CoV-2 is essential for developing effective
treatment strategies. Viruses hijack the host metabolism to redirect the resources for their …
treatment strategies. Viruses hijack the host metabolism to redirect the resources for their …
Role of arachidonic cascade in COVID-19 infection: A review
Abstract The World Health Organization has described the 2019 Coronavirus disease
caused by an influenza-like virus called SARS-CoV-2 as a pandemic. Millions of people …
caused by an influenza-like virus called SARS-CoV-2 as a pandemic. Millions of people …
[HTML][HTML] Decreased oxidative stress and altered urinary oxylipidome by intravenous omega-3 fatty acid emulsion in a randomized controlled trial of older subjects …
Proinflammatory bioactive lipid mediators and oxidative stress are increased in coronavirus
disease 2019 (COVID-19). The randomized controlled single-blind trial COVID-Omega-F …
disease 2019 (COVID-19). The randomized controlled single-blind trial COVID-Omega-F …
[HTML][HTML] AI drug discovery screening for COVID-19 reveals zafirlukast as a repurposing candidate
M Delijewski, J Haneczok - Medicine in Drug Discovery, 2021 - Elsevier
Aims Over the past few years, AI has been considered as potential important area for
improving drug development and in the current urgent need to fight the global COVID-19 …
improving drug development and in the current urgent need to fight the global COVID-19 …
Leukotrienes in innate immunity: still underappreciated after all these years?
CH Serezani, M Divangahi… - The Journal of …, 2023 - journals.aai.org
Leukotrienes (LTs) are lipid mediators derived from the 5-lipoxygenase pathway of
arachidonate metabolism. Though best known for their role in asthma, they have broad …
arachidonate metabolism. Though best known for their role in asthma, they have broad …