Disentangling the complexity of nutrition, frailty and gut microbial pathways during aging: a focus on hippuric acid

A Ticinesi, A Guerra, A Nouvenne, T Meschi, S Maggi - Nutrients, 2023 - mdpi.com
Hippuric acid (HA) is a metabolite resulting from the hepatic glycine conjugation of benzoic
acid (BA) or from the gut bacterial metabolism of phenylalanine. BA is generally produced by …

Structured long-chain omega-3 fatty acids for improvement of cognitive function during aging

I Mora, L Arola, A Caimari, X Escoté… - International journal of …, 2022 - mdpi.com
Although the human lifespan has increased in the past century owing to advances in
medicine and lifestyle, the human healthspan has not kept up the same pace, especially in …

Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging–from theory to practice

C Luís, AT Maduro, P Pereira, JJ Mendes… - Frontiers in …, 2022 - frontiersin.org
Aging is a natural physiological process, but one that poses major challenges in an
increasingly aging society prone to greater health risks such as diabetes, cardiovascular …

Washed microbiota transplantation improves patients with metabolic syndrome in South China

L Wu, XJ Lu, DJ Lin, WJ Chen, XY Xue, T Liu… - Frontiers in Cellular …, 2022 - frontiersin.org
Background Metabolic syndrome (MS) is a growing public health problem worldwide. The
clinical impact of fecal microbiota transplantation (FMT) from healthy donors in MS patients …

Gut microbiota as an antioxidant system in centenarians associated with high antioxidant activities of gut-resident Lactobacillus

L Wu, X Xie, Y Li, T Liang, H Zhong, L Yang… - npj Biofilms and …, 2022 - nature.com
The gut microbiota plays an important role in human health and longevity, and the gut
microbiota of centenarians shows unique characteristics. Nowadays, most microbial …

[HTML][HTML] Combination of the biomarkers for aging and cancer?-Challenges and current status

D Li, F Ju, H Wang, C Fan, JC Jacob, S Gul… - Translational …, 2023 - Elsevier
The proportion of patients diagnosed with cancer has been shown to rise with the increasing
aging global population. Advanced age is a major risk factor for morbidity and mortality in …

The role of SOX transcription factors in ageing and age-related diseases

M Stevanovic, A Lazic, M Schwirtlich… - International Journal of …, 2023 - mdpi.com
The quest for eternal youth and immortality is as old as humankind. Ageing is an inevitable
physiological process accompanied by many functional declines that are driving factors for …

Washed microbiota transplantation improves patients with high blood glucose in South China

L Wu, MQ Li, YT Xie, Q Zhang, XJ Lu, T Liu… - Frontiers in …, 2022 - frontiersin.org
Background and Aims Although fecal microbiota transplantation (FMT) from healthy donors
has been shown to have hypoglycemic effects in animal models of diabetes, its clinical …

Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context

V Robin, A Bodein, MP Scott-Boyer… - Frontiers in Molecular …, 2022 - frontiersin.org
At the heart of the cellular machinery through the regulation of cellular functions, protein–
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …

[HTML][HTML] OMICmAge: An integrative multi-omics approach to quantify biological age with electronic medical records

Q Chen, VB Dwaraka, N Carreras-Gallo, K Mendez… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Biological aging is a multifactorial process involving complex interactions of cellular and
biochemical processes that is reflected in omic profiles. Using common clinical laboratory …