The vaginal microbiome is an intricate and dynamic microecosystem that constantly
undergoes fluctuations during the female menstrual cycle and the woman's entire life. A …

Infectious diseases and infections remain a leading cause of death in low-income countries
and a major risk to vulnerable groups, such as infants and the elderly. The immune system …

Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …

Individuals vary widely in their responses to medicinal drugs, which can be dangerous and
expensive owing to treatment delays and adverse effects. Although increasing evidence …

Emerging evidence indicates a central role for the microbiome in immunity. However, causal
evidence in humans is sparse. Here, we administered broad-spectrum antibiotics to healthy …

The microbiome plays a key role in health and disease, and there has been considerable
interest in therapeutic targeting of the microbiome as well as mining this rich resource in …

Viral infections continue to cause considerable morbidity and mortality around the world.
Recent rises in these infections are likely due to complex and multifactorial external drivers …

Bacterial vaginosis (BV) is a common yet poorly understood vaginal condition that has
become a major focus of HIV transmission and immunology research. Varied terminologies …

The microorganisms of the vaginal tract are critical for vaginal and reproductive health.
However, the regulation of these microorganisms is not well understood. Therefore, we …

Fecal microbiota transplantation (FMT) has become a research focus of biomedicine and
clinical medicine in recent years. The clinical response from FMT for different diseases …