Favipiravir, also known as T-705, is an antiviral drug that has been approved in 2014 in Japan to treat pandemic influenza virus infections. The drug is converted intracellularly into …
R Boudewijns, HJ Thibaut, SJF Kaptein, R Li… - Nature …, 2020 - nature.com
Emergence of SARS-CoV-2 causing COVID-19 has resulted in hundreds of thousands of deaths. In search for key targets of effective therapeutics, robust animal models mimicking …
MA Casel, SJ Park, YK Choi - Experimental & molecular medicine, 2021 - nature.com
An emerging infectious disease first identified in central China in 2009, severe fever with thrombocytopenia syndrome (SFTS) was found to be caused by a novel phlebovirus. Since …
JW Seo, D Kim, N Yun, DM Kim - Viruses, 2021 - mdpi.com
Severe fever with thrombocytopenia syndrome (SFTS) is an acute febrile illness characterized by fever, leukopenia, thrombocytopenia, and gastrointestinal symptoms such …
BE Dawes, B Kalveram, T Ikegami, T Juelich… - Scientific reports, 2018 - nature.com
Nipah and Hendra viruses are recently emerged bat-borne paramyxoviruses (genus Henipavirus) causing severe encephalitis and respiratory disease in humans with fatality …
AC Brault, HM Savage, NK Duggal, RJ Eisen… - Viruses, 2018 - mdpi.com
First identified in two Missouri farmers exhibiting low white-blood-cell and platelet counts in 2009, Heartland virus (HRTV) is genetically closely related to severe fever with …
J Miao, LS Chard, Z Wang, Y Wang - Frontiers in immunology, 2019 - frontiersin.org
Infectious diseases still remain one of the biggest challenges for human health. In order to gain a better understanding of the pathogenesis of infectious diseases and develop effective …
K Suemori, M Saijo, A Yamanaka… - PLoS Neglected …, 2021 - journals.plos.org
Severe fever with thrombocytopenia syndrome (SFTS) is a bunyavirus infection with high mortality. Favipiravir has shown effectiveness in preventing and treating SFTS virus (SFTSV) …
M Saijo - Journal of infection and chemotherapy, 2018 - Elsevier
Severe fever with thrombocytopenia syndrome (SFTS) caused by SFTS virus (SFTSV), a novel phlebovirus, was reported to be endemic to central and northeastern PR China and …