Epigenomic modifications of the brain-derived neurotrophic factor (BDNF) gene have been
postulated to underlie the pathogenesis of neurodevelopmental, psychiatric, and …

Deciphering cell-type heterogeneity is crucial for systematically understanding tissue
homeostasis and its dysregulation in diseases. Computational deconvolution is an efficient …

Epigenetic research in post-traumatic stress disorder (PTSD) is essential, given that
environmental stressors and fear play such a crucial role in its development. As such, it may …

Background Genome-wide DNA methylation (DNAme) profiling of the placenta with Illumina
Infinium Methylation bead arrays is often used to explore the connections between in utero …

Tobacco use is a major modifiable risk factor for adverse health outcomes, including cancer,
and elicits profound epigenetic changes thought to be associated with long-term cancer risk …

Estrogen affects adipose tissue function. Therefore, this study aimed at assessing changes
in the transcriptional activity of estrogen receptor (ER) α and β genes (ESR1 and ESR2 …

Background During aging, the human methylome undergoes both differential and variable
shifts, accompanied by increased entropy. The distinction between variably methylated …

Background Due to interindividual variation in the cellular composition of the human cortex,
it is essential that covariates that capture these differences are included in epigenome-wide …

Deconvolution methods infer quantitative cell type estimates from bulk measurement of
mixed samples including blood and tissue. DNA methylation sequencing measures multiple …

Anxiety Disorders (ANX) such as panic disorder, generalized anxiety disorder, and phobias,
are highly prevalent conditions that are moderately heritable. Evidence suggests that DNA …