Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat
different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to …

Ovarian cancer (OvCa) develops asymptomatically until it reaches the advanced stages with
metastasis, chemoresistance, and poor prognosis. Our review focuses on the analysis of …

As the standard treatments for cancer, chemotherapy and radiotherapy have been widely
applied to clinical practice worldwide. However, the resistance to cancer therapies is a major …

Pharmacokinetics (PK) is the study of the absorption, distribution, metabolism, and excretion
(ADME) processes of a drug. Understanding PK properties is essential for drug development …

Pancreatic cancer is one of the most common causes of cancer death in the world due to the
lack of early symptoms, metastasis occurrence and chemoresistance. Therefore, early …

Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …

The Human Genome Project led to the discovery that about 80% of our DNA is transcribed in
RNA molecules. Only 2% of the human genome is translated into proteins, the rest mostly …

Long noncoding RNAs (lncRNAs), longer than 200 nucleotides in length, play important
roles in the development and progression of various cancers. An increasing number of …

Long-noncoding RNAs (lncRNAs) have been shown to participate in sensitizing or de-
sensitizing cancer cells to chemical drugs during cancer therapeutics. Notably, a plethora of …