SARS-CoV-2 is the virus responsible for the COVID-19 pandemic. The genome of SARS-
CoV-2 encodes nine accessory proteins that are involved in host-pathogen interaction …

The COVID-19 pandemic has resulted in upwards of 6.8 million deaths over the past three
years, and the frequent emergence of variants continues to strain global health. Although …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of
2019 and caused the devastating global pandemic of coronavirus disease 2019 (COVID …

The number of genetic variations in the SARS-CoV-2 genome has been increasing primarily
due to continuous viral mutations. Here, we report that the human APOBEC3A (A3A) cytidine …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs)
possess mutations that confer resistance to neutralizing antibodies within the Spike protein …

Knockout of the ORF8 protein has repeatedly spread through the global viral population
during SARS-CoV-2 evolution. Here we use both regional and global pathogen sequencing …

Coronavirus porcine epidemic diarrhea virus (PEDV) is classified in the genus
Alphacoronavirus, family Coronaviridae that encodes the only accessory protein, ORF3 …

Small animal models have been a challenge for the study of SARS-CoV-2 transmission, with
most investigators using golden hamsters or ferrets. Mice have the advantages of low cost …

Coronaviruses (CoVs) are enveloped and positive-stranded RNA viruses with a large
genome (∼ 30kb). CoVs include essential genes, such as the replicase and four genes …

Coronavirus disease 2019 is a respiratory infectious disease caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Evidence on the pathogenesis of SARS …