[HTML][HTML] Aging and cancer

L Montégut, C López-Otín, G Kroemer - Molecular Cancer, 2024 - Springer
Aging and cancer exhibit apparent links that we will examine in this review. The null
hypothesis that aging and cancer coincide because both are driven by time, irrespective of …

[HTML][HTML] Current and future immunotherapeutic approaches in pancreatic cancer treatment

P Farhangnia, H Khorramdelazad, H Nickho… - Journal of Hematology & …, 2024 - Springer
Pancreatic cancer is a major cause of cancer-related death, but despondently, the outlook
and prognosis for this resistant type of tumor have remained grim for a long time. Currently, it …

[HTML][HTML] Integrative analysis of senescence-related genes identifies robust prognostic clusters with distinct features in hepatocellular carcinoma

S Liu, Y Meng, Y Zhang, L Qiu, X Wan, X Yang… - Journal of Advanced …, 2024 - Elsevier
Introduction Senescence refers to a state of permanent cell growth arrest and is regarded as
a tumor suppressive mechanism, whereas accumulative evidence demonstrate that …

[HTML][HTML] MOST wanted: navigating the MAPK-OIS-SASP-tumor microenvironment axis in primary pediatric low-grade glioma and preclinical models

R Sigaud, T Brummer, D Kocher, T Milde, F Selt - Child's Nervous System, 2024 - Springer
Understanding the molecular and cellular mechanisms driving pediatric low-grade glioma
(pLGG)—the most prevalent brain tumor in children—is essential for the identification and …

[HTML][HTML] Cellular senescence and nanoparticle-based therapies: Current developments and perspectives

A Henschke, A Mielcarek, B Grześkowiak… - Nanotechnology …, 2024 - degruyter.com
The timing and location of senescent cells in vivo is a leading candidate explanation for
human aging. A rapidly developing scientific field with the potential to slow the aging …

Therapy-induced cellular senescence: Potentiating tumor elimination or driving cancer resistance and recurrence?

Y Liu, I Lomeli, SJ Kron - 2024 - preprints.org
Cellular senescence has recently been recognized as a hallmark of cancer, reflecting its
association with aging and inflammation, its role as a response to deregulated proliferation …