Balanced crystalloids versus saline in critically ill adults—a systematic review with meta-analysis

NE Hammond, FG Zampieri, GL Di Tanna… - NEJM …, 2022 - evidence.nejm.org
Background The comparative efficacy and safety of balanced crystalloid solutions and saline
for fluid therapy in critically ill adults remain uncertain. Methods We systematically reviewed …

Fluid therapy for critically ill adults with sepsis: a review

FG Zampieri, SM Bagshaw, MW Semler - Jama, 2023 - jamanetwork.com
Importance Approximately 20% to 30% of patients admitted to an intensive care unit have
sepsis. While fluid therapy typically begins in the emergency department, intravenous fluids …

Restriction of intravenous fluid in ICU patients with septic shock

TS Meyhoff, PB Hjortrup, J Wetterslev… - … England Journal of …, 2022 - Mass Medical Soc
Background Intravenous fluids are recommended for the treatment of patients who are in
septic shock, but higher fluid volumes have been associated with harm in patients who are …

Balanced crystalloid solution versus saline in deceased donor kidney transplantation (BEST-Fluids): a pragmatic, double-blind, randomised, controlled trial

MG Collins, MA Fahim, EM Pascoe, CM Hawley… - The Lancet, 2023 - thelancet.com
Background Delayed graft function (DGF) is a major adverse complication of deceased
donor kidney transplantation. Intravenous fluids are routinely given to patients receiving a …

[HTML][HTML] How I personalize fluid therapy in septic shock?

X Monnet, C Lai, JL Teboul - Critical Care, 2023 - Springer
During septic shock, fluid therapy is aimed at increasing cardiac output and improving tissue
oxygenation, but it poses two problems: it has inconsistent and transient efficacy, and it has …

Association between type of fluid received prior to enrollment, type of admission, and effect of balanced crystalloid in critically ill adults: a secondary exploratory …

FG Zampieri, FR Machado, RS Biondi… - American Journal of …, 2022 - atsjournals.org
Rationale: The effects of balanced crystalloid versus saline on clinical outcomes for ICU
patients may be modified by the type of fluid that patients received for initial resuscitation …

AASLD Practice guidance on Acute-on-chronic liver failure and the management of critically Ill patients with cirrhosis

CJ Karvellas, JS Bajaj, PS Kamath, L Napolitano… - Hepatology, 2024 - journals.lww.com
The clinical stages of cirrhosis have traditionally been divided into a compensated phase
with no complications and a decompensated phase that manifests with complications of …

[HTML][HTML] Management of sepsis and septic shock: what have we learned in the last two decades?

S Kamath, H Hammad Altaq, T Abdo - Microorganisms, 2023 - mdpi.com
Sepsis is a clinical syndrome encompassing physiologic and biological abnormalities
caused by a dysregulated host response to infection. Sepsis progression into septic shock is …

[HTML][HTML] Pathophysiology of fluid administration in critically ill patients

A Messina, J Bakker, M Chew, D De Backer… - Intensive care medicine …, 2022 - Springer
Fluid administration is a cornerstone of treatment of critically ill patients. The aim of this
review is to reappraise the pathophysiology of fluid therapy, considering the mechanisms …

Sepsis-associated acute kidney injury—treatment standard

A Zarbock, JL Koyner, H Gomez… - Nephrology Dialysis …, 2024 - academic.oup.com
Sepsis is a host's deleterious response to infection, which could lead to life-threatening
organ dysfunction. Sepsis-associated acute kidney injury (SA-AKI) is the most frequent …