Since 2015, stroke has become the leading cause of death and disability in China, posing a
significant threat to the health of its citizens as a major chronic non-communicable disease …

The rapid development of such research field as multi-omics and artificial intelligence (AI)
has made it possible to acquire and analyze the multi-dimensional big data of human …

Background We aimed to determine the incidence and disability-adjusted life-years (DALYs)
of neurological disorders worldwide from 1990 to 2019. Methods We obtained age …

Electroacupuncture (EA) and induced pluripotent stem cell (iPSC)-derived small
extracellular vesicles (iPSC-EVs) have substantial beneficial effects on ischemic stroke …

Abstract Background: Menaquinone-4 (MK-4), the isoform of vitamin K2 in the brain, exerts
neuroprotective effects against a variety of central nervous system disorders. This study …

To our knowledge, the adoption of Learning Health System (LHS) concepts or approaches
for improving stroke care, patient outcomes, and value have not previously been …

Background: It is unclear whether sodium intake had similar effects on mortality of stroke
subtypes. The purpose of this study is to compare the long-term trends in mortality of stroke …

Stroke is characterized by high morbidity, high mortality and high disability rate, which is a
major health problem worldwide. However, most community-based studies report a lack of …

Post-stroke depression (PSD) is a frequent and disabling complication of stroke that affects
up to one-third of stroke survivors. The pathophysiology of PSD involves multiple …

Introduction High‐mobility group box 1 protein (HMGB1) is extensively involved in causing
ischemic stroke, pathological damage of ischemic brain injury, and neural tissue repair after …