FR Balkwill, F Burke - Immunology today, 1989 - cell.com
These charts are primarily for reference but they allow US to make some preliminary conclusions abotit the cflokine network:(l) Ail the cytokines in this list have growth factor …
Discussions of eosinophils are often descriptions of end‐stage effector cells with destructive capabilities mediated predominantly by released cytotoxic cationic granule proteins …
LA Dent, M Strath, AL Mellor… - The Journal of …, 1990 - rupress.org
Experiments in vitro suggest that although interleukin 5 (IL-5) stimulates the late stages of eosinophil differentiation, other cytokines are required for the generation of eosinophil …
Protection against pathogens is a prerequisite for survival of most organisms. To cope with this continuous challenge, complex defense mechanisms have evolved. The construction …
K Takatsu - Proceedings of the Japan Academy, Series B, 2011 - jstage.jst.go.jp
While interleukin-5 (IL-5) is initially identified by its ability to support the growth and terminal differentiation of mouse B cells in vitro into antibody-secreting cells, recombinant IL-5 exerts …
C Pelaia, C Calabrese, A Vatrella… - BioMed research …, 2018 - Wiley Online Library
Asthma is a very frequent chronic airway disease that includes many different clinical phenotypes and inflammatory patterns. In particular, eosinophilic bronchial inflammation is …
J Tavernier, R Devos, S Cornelis, T Tuypens… - Cell, 1991 - cell.com
Summary cDNA clones encoding two receptor proteins involved in the binding of human interleukin 5 (hlL5) have been isolated. A first class codes for an IL5specific chain (hILLflu) …
R Nishinakamura, N Nakayama, Y Hirabayashi… - Immunity, 1995 - cell.com
The receptors for IL-3, GM-CSF, and IL-5 share a common 5 subunit (5c), and mice have an additional IL-3 5 subunit (5~). We have independently generated mice carrying null …
The nervous system, through the production of neuroregulators (neurotransmitters, neuromodulators and neuropeptides) can regulate specific immune system functions, while …