Contributions for classification of platelet rich plasma–proposal of a new classification: MARSPILL

JFSD Lana, J Purita, C Paulus, SC Huber… - Regenerative …, 2017 - Taylor & Francis
Platelet-rich plasma (PRP) has emerged as a significant therapy used in medical conditions
with heterogeneous results. There are some important classifications to try to standardize …

The cytokine network

FR Balkwill, F Burke - Immunology today, 1989 - cell.com
These charts are primarily for reference but they allow US to make some preliminary
conclusions abotit the cflokine network:(l) Ail the cytokines in this list have growth factor …

Eosinophils in health and disease: the LIAR hypothesis

JJ Lee, EA Jacobsen, MP McGarry… - Clinical & …, 2010 - Wiley Online Library
Discussions of eosinophils are often descriptions of end‐stage effector cells with destructive
capabilities mediated predominantly by released cytotoxic cationic granule proteins …

Eosinophilia in transgenic mice expressing interleukin 5.

LA Dent, M Strath, AL Mellor… - The Journal of …, 1990 - rupress.org
Experiments in vitro suggest that although interleukin 5 (IL-5) stimulates the late stages of
eosinophil differentiation, other cytokines are required for the generation of eosinophil …

A primer on cytokines: sources, receptors, effects, and inducers

JH Curfs, JF Meis… - Clinical microbiology …, 1997 - Am Soc Microbiol
Protection against pathogens is a prerequisite for survival of most organisms. To cope with
this continuous challenge, complex defense mechanisms have evolved. The construction …

Interleukin-5 and IL-5 receptor in health and diseases

K Takatsu - Proceedings of the Japan Academy, Series B, 2011 - jstage.jst.go.jp
While interleukin-5 (IL-5) is initially identified by its ability to support the growth and terminal
differentiation of mouse B cells in vitro into antibody-secreting cells, recombinant IL-5 exerts …

Benralizumab: from the basic mechanism of action to the potential use in the biological therapy of severe eosinophilic asthma

C Pelaia, C Calabrese, A Vatrella… - BioMed research …, 2018 - Wiley Online Library
Asthma is a very frequent chronic airway disease that includes many different clinical
phenotypes and inflammatory patterns. In particular, eosinophilic bronchial inflammation is …

A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF

J Tavernier, R Devos, S Cornelis, T Tuypens… - Cell, 1991 - cell.com
Summary cDNA clones encoding two receptor proteins involved in the binding of human
interleukin 5 (hlL5) have been isolated. A first class codes for an IL5specific chain (hILLflu) …

Mice deficient for the IL-3/GM-CSF/IL-5 βc receptor exhibit lung pathology and impaired immune response, while βIL3 receptor-deficient mice are normal

R Nishinakamura, N Nakayama, Y Hirabayashi… - Immunity, 1995 - cell.com
The receptors for IL-3, GM-CSF, and IL-5 share a common 5 subunit (5c), and mice have an
additional IL-3 5 subunit (5~). We have independently generated mice carrying null …

Immunoregulators in the nervous system

CR Plata-Salamán - Neuroscience & Biobehavioral Reviews, 1991 - Elsevier
The nervous system, through the production of neuroregulators (neurotransmitters,
neuromodulators and neuropeptides) can regulate specific immune system functions, while …