Interleukins: biological properties and therapeutic potential

RE Elmslie, SW Dow, GK Ogilvie - Journal of veterinary internal …, 1991 - Wiley Online Library
Interleukins are biologically active glycoproteins derived primarily from activated
lymphocytes and macrophages. Tremendous insight into the biochemical and biological …

Molecular structure of the IL-3, GM-CSF and IL-5 receptors

A Miyajima - Stem Cells, 1992 - academic.oup.com
Reconstitution of high-affinity receptors using molecularly cloned receptor subunits has
revealed that the high-affinity receptors for interleukin 3 (IL-3), granulocyte-macrophage …

IL-5 induces proliferation and activation of microglia via an unknown receptor

SM Liva, J de Vellis - Neurochemical research, 2001 - Springer
While the effects of interleukin-3 (IL-3) and granulocyte macrophage-colony stimulating
factor (GM-CSF) on microglia are well documented, very little is known about the effects of a …

Detection of humoral and cellular immune responses in buffaloes naturally infected with sarcocystosis with risk factor assessment

EE El Shanawany, SA Nassar, EB Ata - Acta veterinaria, 2019 - sciendo.com
Sarcocystosis is a silent, parasitic disease which affects various animal species and causes
significant economic losses. It is caused by a number of different intracellular Sarcocystis …

Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA …

T Yamagata, J Nishida, R Sakai, T Tanaka… - … and cellular biology, 1995 - Taylor & Francis
Interleukin-5 (IL-5) is produced by T lymphocytes and known to support B-cell growth and
eosinophilic differentiation of the progenitor cells. Using ATL-16T cells which express IL-5 …

The RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Inactivate the Th2 Cytokines Interleukin-4 and Interleukin-5

V Tam, NM O'Brien-Simpson, YY Chen… - Infection and …, 2009 - Am Soc Microbiol
ABSTRACT The RgpA-Kgp proteinase-adhesin complexes are a primary virulence factor of
Porphyromonas gingivalis, a major pathogen in the development of chronic periodontitis …

Interleukin 5 regulation of peritoneal Ly‐1 B lymphocyte proliferation, differentiation and autoantibody secretion

GD Wetzel - European journal of immunology, 1989 - Wiley Online Library
The in vitro effects of recombinant interleukin (IL) 5 on proliferation and maturation of mouse
Ly‐1 B cells were studied. Most freshly isolated peritoneal Ly‐1 B cells expressed high …

[HTML][HTML] Serum IL-5 levels predict HBsAg seroclearance in patients treated with Nucleos (t) ide analogues combined with pegylated interferon

P Wang, Z Mo, Y Zhang, C Guo, TK Chikede… - Frontiers in …, 2023 - frontiersin.org
Background Knowing about cytokine profile contributes to clarify the underling immune
mechanism of HBsAg seroclearance rate increase. This study aims to investigate cytokine …

Biological and molecular characteristics of interleukin-5 and its receptor

S Karlen, MLD Boer, RJ Lipscombe… - International reviews …, 1998 - Taylor & Francis
Interleukin-5 (IL5) is a T cell-derived cytokine involved in the pathogenesis of atopic
diseases. It specifically controls the production, the activation and the localization of …

Role of sugar chains in the in‐vitro activity of recombinant human interleukin 5

S Kodama, M TSUJIMOTO, N Tsuruoka… - European journal of …, 1993 - Wiley Online Library
The structures of O‐linked sugar chains of recombinant human interleukin 5 (rhIL‐5)
produced by Chinese hamster ovary cells were determined employing high‐performance …